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Invitrogen
SMC2 Polyclonal Antibody
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FIGURE: 1 / 1
SMC2 Antibody (PA5-110399) in WB
Western blot analysis of SMC2 in extracts of various cells. Samples were incubated with SMC2 Polyclonal antibody (Product # PA5-110399) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-110399
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 700-900 of human SMC2 (NP_006435.2).
Conjugate
Form
Liquid
Concentration
0.66 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855810
Product Specific Information
Immunogen sequence: EELAGLKNTA EKYRQLKQQW EMKTEEADLL QTKLQQSSYH KQQEELDALK KTIEESEETL KNTKEIQRKA EEKYEVLENK MKNAEAERER ELKDAQKKLD CAKTKADASS KKMKEKQQEV EAITLELEEL KREHTSYKQQ LEAVNEAIKS YESQIEVMAA EVAKNKESVN KAQEEVTKQK EVITAQDTVI KAKYAEVAKH K
Target Information
CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behavior of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in humar cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAP E; Chromosome-associated protein E; FGF-inducible protein 16; fibroblast growth factor inducible 16; FLJ10093; hCAP-E; SMC protein 2; SMC2 (structural maintenance of chromosomes 2, yeast)-like 1; SMC2 protein; SMC2 structural maintenance of chromosomes 2-like 1; structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E; Structural maintenance of chromosomes protein 2; XCAP-E homolog
Gene Aliases: 5730502P04Rik; AI255214; AW545314; CAP-E; CAPE; Fin16; PRO0324; SMC-2; SMC2; SMC2L1
UniProt ID: (Human) O95347, (Mouse) Q8CG48
Entrez Gene ID: (Human) 10592, (Mouse) 14211
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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