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          • Primary Antibodies ›
          • SMCHD1 Antibodies

          Invitrogen

          SMCHD1 Polyclonal Antibody

          Advanced Verification
          View all (9) SMCHD1 antibodies

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          Datasheet
          Protocols
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          Datasheet
          Protocols
          Questions & Answers

          Cite SMCHD1 Polyclonal Antibody

          • Antibody Testing Data (6)
          • Advanced Verification (1)
          SMCHD1 Antibody in Immunocytochemistry (ICC/IF)
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          SMCHD1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          SMCHD1 Antibody (PA5-58788) in ICC/IF

          Immunofluorescent staining of SMCHD1 in human cell line U-2 OS using a SMCHD1 Polyclonal Antibody (Product # PA5-58788) shows localization to nucleoplasm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          SMCHD1 Antibody in Immunocytochemistry (ICC/IF)
          SMCHD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMCHD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMCHD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMCHD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMCHD1 Antibody in Western Blot (WB)
          SMCHD1 Antibody

          Product Details

          PA5-58788

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human SMCHD1. Recombinant protein control fragment (Product #RP-98295).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2647622

          Product Specific Information

          Immunogen sequence: DNGRGMTSKQ LNNWAVYRLS KFTRQGDFES DHSGYVRPVP VPRSLNSDIS YFGVGGKQAV FFVGQSARMI SKPADSQDVH ELVLSKED

          Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.

          Target Information

          Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: SMC hinge domain-containing protein 1; Structural maintenance of chromosomes flexible hinge domain-containing protein 1

          View more View less

          Gene Aliases: KIAA0650; SMCHD1

          View more View less

          UniProt ID: (Human) A6NHR9

          View more View less

          Entrez Gene ID: (Human) 23347

          View more View less

          Function(s)
          ATP binding
          Process(es)
          chromosome organization inactivation of X chromosome by DNA methylation
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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