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Invitrogen
SMG5 Polyclonal Antibody
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Product Details
PA5-44295
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human SMG5 (aa 1-50).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2576490
Product Specific Information
Peptide sequence: MSQGPPTGES SEPEAKVLHT KRLYRAVVEA VHRLDLILCN KTAYQEVFKP
Sequence homology: Cow: 100%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rat: 86%
Target Information
SMG5 plays a role in nonsense-mediated mRNA decay. SMG5 does not have RNase activity by itself. SMG5 promotes dephosphorylation of RENT1. SMG5 is necessary for TERT activity.SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).[supplied by OMIM].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EST1 telomerase component homolog B; EST1-like protein B; Est1p-like protein B; ever shorter telomeres 1B; FLJ34864; hSMG-5; LPTS interacting protein; LPTS-interacting protein; LPTS-RP1; Nonsense-mediated mRNA decay factor SMG5; RP11-54H19.7; SMG-5 homolog; smg-5 homolog, nonsense mediated mRNA decay factor; SMG5 nonsense mediated mRNA decay factor
Gene Aliases: EST1B; KIAA1089; LPTS-RP1; LPTSRP1; SMG-5; SMG5
UniProt ID: (Human) Q9UPR3
Entrez Gene ID: (Human) 23381
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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