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Invitrogen
SMG6 Polyclonal Antibody
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Product Details
PA5-60165
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SMG6. Recombinant protein control fragment (Product #RP-91833).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2647637
Product Specific Information
Immunogen sequence: MAEGLERVRI SASELRGILA TLAPQAGSRE NMKELKEARP RKDNRRPDLE IYKPGLSRLR NKPKIKEPPG SEEFKDEIVN DRDCSAVENG TQPVKDVCKE LNNQEQNGPI DP
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 85%.
Target Information
This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EST1 telomerase component homolog A; Ever shorter telomeres 1A; hEST1A; hSmg5/7a; Nonsense mediated mRNA decay factor SMG6; Smg-6 homolog; smg-6 homolog, nonsense mediated mRNA decay factor; SMG6 nonsense mediated mRNA decay factor; telomerase subunit EST1A; Telomerase-binding protein EST1A
Gene Aliases: C17orf31; EST1A; hSMG5/7a; KIAA0732; SMG-6; SMG6
UniProt ID: (Human) Q86US8
Entrez Gene ID: (Human) 23293
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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