Proteintech

SMMHC Polyclonal Antibody

FIGURE: 1 / 4

SMMHC Antibody (18569-1-AP) in WB

Mouse bladder tissue were subjected to SDS PAGE followed by western blot with 18569-1-AP (SMMHC antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

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Product Details

18569-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SMMHC Fusion Protein Ag13391 (1-351 aa encoded by BC101677)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.16 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAQKGQLSD DEKFLFVDKN FINSPVAQAD WAAKRLVWVP SEKQGFEAAS IKEEKGDEVV VELVENGKKV TVGKDDIQKM NPPKFSKVED MAELTCLNEA SVLHNLRERY FSGLIYTYSG LFCVVVNPYK HLPIYSEKIV DMYKGKKRHE MPPHIYAIAD TAYRSMLQDR EDQSILCTGE SGAGKTENTK KVIQYLAVVA SSHKGKKDTS ITGELEKQLL QANPILEAFG NAKTVKNDNS SRFGKFIRIN FDVTGYIVGA NIETYLLEKS RAIRQARDER TFHIFYYMIA GAKEKMRSDL LLEGFNNYTF LSNGFVPIPA AQDDEMFQET VEAMAIMGFS EEEQLSILKV VS (1-351 aa encoded by BC101677)

Target Information

SM-MHC is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmently regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

miRNA‑92a inhibits vascular smooth muscle cell phenotypic modulation and may help prevent in‑stent restenosis.

Molecular medicine reports

Jiang F,Zhang B,Zhang X,Zhang R,Lu Q,Shi F,Xu J,Deng L

Wed Feb 01 00:00:00 UTC 2023

Theaflavin-3,3'-Digallate from Black Tea Inhibits Neointima Formation Through Suppression of the PDGFRβ Pathway in Vascular Smooth Muscle Cells.

Frontiers in pharmacology

Wu Y,Chen M,Chen Z,Shu J,Zhang L,Hu J,Yu H,Huang K,Liang M

Sun Jul 31 00:00:00 UTC 2022

Sphingosine 1-phosphate receptor 2 promotes erythrocyte clearance by vascular smooth muscle cells in intraplaque hemorrhage through MFG-E8 production.

Cellular signalling

Pan D,Wu W,Zuo G,Xie X,Li H,Ren X,Kong C,Zhou W,Zhang Z,Waterfall M,Chen S

Sat Oct 01 00:00:00 UTC 2022

LINC01278 Sponges miR-500b-5p to Regulate the Expression of ACTG2 to Control Phenotypic Switching in Human Vascular Smooth Muscle Cells During Aortic Dissection.

Journal of the American Heart Association

Wang W,Liu Q,Wang Y,Piao H,Zhu Z,Li D,Wang T,Liu K

Tue May 04 00:00:00 UTC 2021

Depiction of Aging-Based Molecular Phenotypes With Diverse Clinical Prognosis and Immunological Features in Gastric Cancer.

Frontiers in medicine

He F,Ding H,Zhou Y,Wang Y,Xie J,Yang S,Zhu Y

Sun May 01 00:00:00 UTC 2022

5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Promotes Phenotypic Switching from Dedifferentiated to Differentiated Phenotype via Reactive Oxygen Species and p38 Mitogen-Activated Protein Kinase in Vascular Smooth Muscle Cells.

Ultrasound in medicine & biology

Dan J,Sun X,Li W,Zhang Y,Li X,Xu H,Li Z,Tian Z,Guo S,Yao J,Gao W,Tian Y

Mon Jun 01 00:00:00 UTC 2015

Ultrasound in medicine & biology

Dan J,Sun X,Li W,Zhang Y,Li X,Xu H,Li Z,Tian Z,Guo S,Yao J,Gao W,Tian Y

Mon Jun 01 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: myh11 {ECO:0000312|RGD:3136}; Myosin heavy chain 11; myosin heavy chain 11, smooth muscle; myosin heavy chain 21; Myosin heavy chain, smooth muscle isoform; myosin, heavy chain 11, smooth muscle; myosin, heavy polypeptide 11, smooth muscle; Myosin-11; SMMHC; smooth muscle myosin heavy chain

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Gene Aliases: AAT4; AV071570; FAA4; KIAA0866; MYH11; SM1; SM2; SMHC; SMMHC

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UniProt ID: (Human) P35749

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Entrez Gene ID: (Human) 4629, (Rat) 24582, (Mouse) 17880

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Function(s)

motor activity protein binding calmodulin binding ATP binding structural constituent of muscle actin filament binding actin binding nucleotide binding

Process(es)

smooth muscle contraction metabolic process elastic fiber assembly cardiac muscle fiber development muscle contraction skeletal muscle myosin thick filament assembly mitophagy in response to mitochondrial depolarization

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SMMHC Polyclonal Antibody

SMMHC Antibody (18569-1-AP) in WB

Product Details

18569-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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