Proteintech

SMMHC Polyclonal Antibody

SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SMMHC Antibody (21404-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded Human colon tissue slide using (Product # 21404-1-AP) SMMHC antibody at dilution of 1:2,000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

SMMHC Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

Product Image Gallery

Product Details

21404-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 26 publications 26 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 9 publications 9 publications

Flow Cytometry (Flow)

Assay-dependent

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SMMHC Fusion Protein Ag16114 (1208-1316 aa encoded by BC104906)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: LTEQLEQFK RAKANLDKNK QTLEKENADL AGELRVLGQA KQEVEHKKKK LEAQVQELQS KCSDGERARA ELNDKVHKLQ NEVESVTGML NEAEGKAIKL AKDVASLSSQ (1208-1316 aa encoded by BC104906)

Target Information

SM-MHC is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmently regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

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Fate mapping RNA-sequencing reveal Malat1 regulates Sca1⁺ progenitor cells to vascular smooth muscle cells transition in vascular remodeling.

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Thu Apr 06 00:00:00 UTC 2023

Fate mapping RNA-sequencing reveal Malat1 regulates Sca1⁺ progenitor cells to vascular smooth muscle cells transition in vascular remodeling.

Cellular and molecular life sciences : CMLS

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Fate mapping RNA-sequencing reveal Malat1 regulates Sca1⁺ progenitor cells to vascular smooth muscle cells transition in vascular remodeling.

Cellular and molecular life sciences : CMLS

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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

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The Hemoglobin Homolog Cytoglobin in Smooth Muscle Inhibits Apoptosis and Regulates Vascular Remodeling.

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Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury.

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Bioinformatics

Protein Aliases: myh11 {ECO:0000312|RGD:3136}; Myosin heavy chain 11; myosin heavy chain 11, smooth muscle; myosin heavy chain 21; Myosin heavy chain, smooth muscle isoform; myosin, heavy chain 11, smooth muscle; myosin, heavy polypeptide 11, smooth muscle; Myosin-11; SMMHC; smooth muscle myosin heavy chain

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Gene Aliases: AAT4; AV071570; FAA4; KIAA0866; MYH11; SM1; SM2; SMHC; SMMHC

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UniProt ID: (Human) P35749

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Entrez Gene ID: (Human) 4629, (Rat) 24582, (Mouse) 17880

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Function(s)

motor activity protein binding calmodulin binding ATP binding structural constituent of muscle actin filament binding actin binding nucleotide binding

Process(es)

smooth muscle contraction metabolic process elastic fiber assembly cardiac muscle fiber development muscle contraction skeletal muscle myosin thick filament assembly mitophagy in response to mitochondrial depolarization

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SMMHC Polyclonal Antibody

SMMHC Antibody (21404-1-AP) in IHC (P)

Product Details

21404-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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