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Invitrogen
SMPD2 Polyclonal Antibody
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FIGURE: 1 / 4
SMPD2 Antibody (PA5-24614) in WB
Western blot analysis of SMPD2 in various lysates. Samples were incubated with SMPD2 polyclonal antibody (Product # PA5-24614) using a dilution of 1:1,000 followed by Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Lane 1: K562 whole cell lysate; Lane 2: SH-SY5Y whole cell lysate. Predicted band size: 48 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Product Details
PA5-24614
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 9-35 amino acids from the N-terminal region of human SMPD2
Conjugate
Form
Liquid
Concentration
1.8 mg/mL
Purification
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2542114
Target Information
Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Lyso-PAF-PLC; Lyso-platelet-activating factor-phospholipase C; N-SMase; Neutral sphingomyelinase; neutral sphingomyelinase 1; NSMA; Sphingomyelin phosphodiesterase 2; sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
Gene Aliases: AW108287; ISC1; NSMASE; NSMASE1; SMPD2
UniProt ID: (Human) O60906, (Mouse) O70572
Entrez Gene ID: (Human) 6610, (Mouse) 20598
sphingomyelin metabolic process
glycosphingolipid metabolic process
response to mechanical stimulus
intracellular signal transduction
ceramide biosynthetic process
positive regulation of ceramide biosynthetic process
lipid metabolic process
sphingolipid metabolic process
positive regulation of apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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