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Invitrogen
SMPD2 Polyclonal Antibody
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FIGURE: 1 / 1
SMPD2 Antibody (PA5-88199) in WB
Western blot analysis of SMPD2 in extracts of various cell lines. Samples were incubated with SMPD2 Polyclonal antibody (Product # PA5-88199) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-88199
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SMPD2 (NP_0030712)
Conjugate
Form
Liquid
Concentration
0.48 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804736
Product Specific Information
Immunogen sequence: AHRVAQAWEL AQFIHHTSKK ADVVLLCGDL NMHPEDLGCC LLKEWTGLHD AYLETRDFKG SEEGNTMVPK NCYVSQQELK PFPFGVRIDY VLYKAVSGFY I; Positive Samples: Mouse liver, Rat liver; Cellular Location: Membrane, Multi-pass membrane protein
Target Information
Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Lyso-PAF-PLC; Lyso-platelet-activating factor-phospholipase C; N-SMase; Neutral sphingomyelinase; neutral sphingomyelinase 1; NSMA; Sphingomyelin phosphodiesterase 2
Gene Aliases: AW108287; nSMase; nSMase1; Smpd2
UniProt ID: (Mouse) O70572, (Rat) Q9ET64
Entrez Gene ID: (Mouse) 20598, (Rat) 83537
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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