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Product Details
PA5-56367
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SMPDL3A. Recombinant protein control fragment (Product #RP-101899).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2647662
Product Specific Information
Immunogen sequence: SPVNSLFVAP AVTPVKSVLE KQTNNPGIRL FQYDPRDYKL LDMLQYYLNL TEANLKGESI WKLEYILTQT YDIEDLQPES LYGLAKQFTI LDSKQFIKYY NYFFVSYDSS ATCDKTCKAF QICAIM
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 76%.
Target Information
Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP (PubMed:25288789, PubMed:26783088). Has in vitro activity with p-nitrophenyl-TMP (PubMed:25288789). Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates (PubMed:25288789, PubMed:26783088). Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine (PubMed:26783088). Does not have sphingomyelin phosphodiesterase activity (PubMed:25288789, PubMed:26783088). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 0610010C24Rik; 2',3'-cGAMP phosphodiesterase SMPDL3A; Acid sphingomyelinase-like phosphodiesterase 3a; ASM-like phosphodiesterase 3a; Cyclic GMP-AMP phosphodiesterase SMPDL3A; sphingomyelin phosphodiesterase acid-like 3A; sphingomyelin phosphodiesterase, acid-like 3A
Gene Aliases: ASM3A; ASML3A; SMPDL3A; yR36GH4.1
UniProt ID: (Human) Q92484
Entrez Gene ID: (Human) 10924
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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