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SNAP-23/SNAP-25 Polyclonal Antibody
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Product Details
OSS00167W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from n-terminal region of mouse Synaptosomal-associated protein 23 conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The antigen shares 90% identity with SNAP-25.
Specificity of this antibody: SNAP-23 and SNAP-25.
Target Information
SNAP23 is an essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. SNAP25 is involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Subcellular Location: SNAP-23: Cell membrane; Peripheral membrane protein. Cell junction; synapse; synaptosome. Note: Mainly localized to the plasma membrane. SNAP-25: Cytoplasm; perinuclear region. Cell membrane; Lipid-anchor. Cell junction; synapse; synaptosome. Note: Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: blind drunk; resistance to inhibitors of cholinesterase 4 homolog; SNAP-23; SNAP-25; SUP; Super protein; Synaptosomal-associated 25 kDa protein; Synaptosomal-associated protein 23; synaptosomal-associated protein 23 kD; Synaptosomal-associated protein 25; synaptosomal-associated protein, 23 kD; synaptosomal-associated protein, 23kD; synaptosomal-associated protein, 23kDa; synaptosomal-associated protein, 25 kDa; synaptosomal-associated protein, 25kDa; synaptosome associated protein 23kDa; synaptosome associated protein 25kDa; Syndet; Vesicle-membrane fusion protein SNAP-23
Gene Aliases: 23kDa; AA408749; bA416N4.2; Bdr; CMS18; dJ1068F16.2; GENA70; HsT17016; RIC-4; RIC4; SEC9; SNAP; SNAP-23; SNAP-25; SNAP-25a; SNAP-25B; SNAP23; SNAP23A; SNAP23B; SNAP25; Sndt; sp; SUP; Syndet
UniProt ID: (Human) O00161, (Human) P60880, (Mouse) O09044, (Rat) O70377, (Rat) P60881, (Mouse) P60879
Entrez Gene ID: (Human) 8773, (Human) 6616, (Mouse) 20619, (Rat) 64630, (Rat) 25012, (Mouse) 20614
exocytosis
neurotransmitter secretion
axonogenesis
long-term memory
regulation of neuron projection development
synaptic vesicle priming
endosomal transport
growth hormone secretion
sleep
synaptic vesicle fusion to presynaptic active zone membrane
positive regulation of insulin secretion
positive regulation of hormone secretion
calcium ion-regulated exocytosis of neurotransmitter
regulation of synapse assembly
long-term synaptic potentiation
regulation of establishment of protein localization
potassium ion transmembrane transport
histamine secretion by mast cell
protein complex assembly
transport
protein transport
vesicle-mediated transport
regulation of exocytosis
membrane fusion
neurotransmitter uptake
chemical synaptic transmission
locomotory behavior
associative learning
glutamate secretion
synaptic vesicle exocytosis
synaptic vesicle docking
regulation of insulin secretion
regulation of ion transmembrane transport
post-Golgi vesicle-mediated transport
vesicle targeting
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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