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Invitrogen
SNAP25 Recombinant Rabbit Monoclonal Antibody (152)
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Product Details
MA5-30893
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
152
Immunogen
Recombinant Human SNAP25 protein (Met1-Gly206)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2786567
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human SNAP25.
Target Information
SNAP25 is a t-SNARE involved in the molecular regulation of neurotransmitter release. It may play a role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. It also regulates plasma membrane recycling through its interaction with CENPF. Mutations in the gene can results in myasthenic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ALMS1; CG17676; CG17884; CG40452; Dmel CG40452; Dmel_CG40452; FLJ23079; HGNC:11132; resistance to inhibitors of cholinesterase 4 homolog; SNAP 25; SNAP-25; snp25; SUP; Super protein; Synaptosomal-associated 25 kDa protein; Synaptosomal-associated protein 25; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25kDa
Gene Aliases: bA416N4.2; CMS18; dJ1068F16.2; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SNAP25; SUP
UniProt ID: (Human) P60880
Entrez Gene ID: (Human) 6616
neurotransmitter uptake
chemical synaptic transmission
neurotransmitter secretion
locomotory behavior
associative learning
regulation of neuron projection development
glutamate secretion
synaptic vesicle exocytosis
synaptic vesicle docking
synaptic vesicle priming
synaptic vesicle fusion to presynaptic active zone membrane
regulation of insulin secretion
long-term synaptic potentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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