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SND1 Polyclonal Antibody

View all (17) SND1 antibodies

Questions & Answers

Questions & Answers

Antibody Testing Data (9)

SND1 Antibody in Immunocytochemistry (ICC/IF)

SND1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 9

SND1 Antibody (10760-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed HeLa cells using 10760-1-AP (SND1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

SND1 Antibody in Immunocytochemistry (ICC/IF)

SND1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SND1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SND1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SND1 Antibody in Western Blot (WB)

SND1 Antibody in Western Blot (WB)

SND1 Antibody in Western Blot (WB)

SND1 Antibody in Western Blot (WB)

SND1 Antibody in Western Blot (WB)

Product Image Gallery

SND1 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of ( -20°C Ethanol ) fixed HeLa cells using 10760-1-AP (SND1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

SND1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of paraffin-embedded Human breast hyperplasia tissue slide using (Product # 10760-1-AP) SND1 antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

SND1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human liver slide using 10760-1-AP ( SND1 Antibody) at dilution of 1:50.

SND1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human liver slide using 10760-1-AP (SND1 Antibody) at dilution of 1:50.

SND1 Antibody in Western Blot (WB) — Various lysates were subjected to SDS PAGE followed by western blot with (Product # 10760-1-AP) SND1 antibody at dilution of 1:8,000 incubated at room temperature for 1.5 hours.

SND1 Antibody in Western Blot (WB) — COLO 320 cells were subjected to SDS PAGE followed by western blot with 10760-1-AP (SND1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

SND1 Antibody in Western Blot (WB) — Jurkat cells were subjected to SDS PAGE followed by western blot with 10760-1-AP (SND1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

SND1 Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 10760-1-AP (SND1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

SND1 Antibody in Western Blot (WB) — WB result of SND1 antibody (10760-1-AP, 1:4000) with si-Control and si-SND1 transfected Jurkat cells.

Product Details

10760-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 7 publications 7 publications

Immunohistochemistry (IHC)

-

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

ChIP assay (ChIP)

-

View 1 publication 1 publication

RNA Immunoprecipitation (RIP)

-

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SND1 Fusion Protein Ag1200 (548-911 aa encoded by BC017180)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This is a rabbit polyclonal antibody raised against near the C-terminus of human SND1.

Immunogen sequence: TCLITFLLA GIECPRGARN LPGLVQEGEP FSEEATLFTK ELVLQREVEV EVESMDKAGN FIGWLHIDGA NLSVLLVEHA LSKVHFTAER SSYYKSLLSA EEAAKQKKEK VWAHYEEQPV EEVMPVLEEK ERSASYKPVF VTEITDDLHF YVQDVETGTQ LEKLMENMRN DIASHPPVEG SYAPRRGEFC IAKFVDGEWY RARVEKVESP AKIHVFYIDY GNREVLPSTR LGTLSPAFST RVLPAQATEY AFAFIQVPQD DDARTDAVDS VVRDIQNTQC LLNVEHLSAG CPHVTLQFAD SKGDVGLGLV KEGLVMVEVR KEKQFQKVIT EYLNAQESAK SARLNLWRYG DFRADDADEF GYSR (548-911 aa encoded by B C017180)

Target Information

SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activator of EBNA-2. It also interacts with EAV, NSP1, GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m⁶A-dependent recognition of Nrf2 mRNA mediated by SND1.

Journal of experimental & clinical cancer research : CR

Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X

Fri May 19 00:00:00 UTC 2023

Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m⁶A-dependent recognition of Nrf2 mRNA mediated by SND1.

Journal of experimental & clinical cancer research : CR

Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X

Fri May 19 00:00:00 UTC 2023

Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m⁶A-dependent recognition of Nrf2 mRNA mediated by SND1.

Journal of experimental & clinical cancer research : CR

Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X

Fri May 19 00:00:00 UTC 2023

Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m⁶A-dependent recognition of Nrf2 mRNA mediated by SND1.

Journal of experimental & clinical cancer research : CR

Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X

Fri May 19 00:00:00 UTC 2023

Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m⁶A-dependent recognition of Nrf2 mRNA mediated by SND1.

Journal of experimental & clinical cancer research : CR

Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X

Fri May 19 00:00:00 UTC 2023

Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m⁶A-dependent recognition of Nrf2 mRNA mediated by SND1.

Journal of experimental & clinical cancer research : CR

Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X

Fri May 19 00:00:00 UTC 2023

Phospho-Tudor-SN coordinates with STAT5 to regulate prolactin-stimulated milk protein synthesis and proliferation of bovine mammary epithelial cells.

Animal biotechnology

Ao J,Ma Z,Li R,Zhang S,Gao X,Zhang M

Tue Nov 01 00:00:00 UTC 2022

Divergent transcriptional regulation of astrocyte reactivity across disorders.

Nature

Burda JE,O'Shea TM,Ao Y,Suresh KB,Wang S,Bernstein AM,Chandra A,Deverasetty S,Kawaguchi R,Kim JH,McCallum S,Rogers A,Wahane S,Sofroniew MV

Wed Jun 01 00:00:00 UTC 2022

Predicting dynamic cellular protein-RNA interactions by deep learning using in vivo RNA structures.

Cell research

Sun L,Xu K,Huang W,Yang YT,Li P,Tang L,Xiong T,Zhang QC

Sat May 01 00:00:00 UTC 2021

Comp34 displays potent preclinical antitumor efficacy in triple-negative breast cancer via inhibition of NUDT3-AS4, a novel oncogenic long noncoding RNA.

Cell death & disease

Hao Q,Wang P,Dutta P,Chung S,Li Q,Wang K,Li J,Cao W,Deng W,Geng Q,Schrode K,Shaheen M,Wu K,Zhu D,Chen QH,Chen G,Elshimali Y,Vadgama J,Wu Y

Fri Dec 11 00:00:00 UTC 2020

The phosphorylation of Tudor-SN mediated by JNK is involved in the regulation of milk protein synthesis induced by prolactin in BMECs.

Journal of cellular physiology

Zhang S,Qi H,Wen XP,Li P,Gao XJ,Ao JX

Wed May 01 00:00:00 UTC 2019

The Tudor SND1 protein is an m⁶A RNA reader essential for replication of Kaposi's sarcoma-associated herpesvirus.

eLife

Baquero-Perez B,Antanaviciute A,Yonchev ID,Carr IM,Wilson SA,Whitehouse A

Thu Oct 24 00:00:00 UTC 2019

The Tudor SND1 protein is an m⁶A RNA reader essential for replication of Kaposi's sarcoma-associated herpesvirus.

eLife

Baquero-Perez B,Antanaviciute A,Yonchev ID,Carr IM,Wilson SA,Whitehouse A

Thu Oct 24 00:00:00 UTC 2019

The Tudor SND1 protein is an m⁶A RNA reader essential for replication of Kaposi's sarcoma-associated herpesvirus.

eLife

Baquero-Perez B,Antanaviciute A,Yonchev ID,Carr IM,Wilson SA,Whitehouse A

Thu Oct 24 00:00:00 UTC 2019

Elevated transcriptional co-activator p102 mediates angiotensin II type 1 receptor up-regulation and extracellular matrix overproduction in the high glucose-treated rat glomerular mesangial cells and isolated glomeruli.

European journal of pharmacology

Wang Z,Ni J,Shao D,Liu J,Shen Y,Zhou L,Huang Y,Yu C,Wang J,Xue H,Lu L

Thu Feb 28 00:00:00 UTC 2013

Novel breast cancer metastasis-associated proteins.

Journal of proteome research

Ho J,Kong JW,Choong LY,Loh MC,Toy W,Chong PK,Wong CH,Wong CY,Shah N,Lim YP

Sun Feb 01 00:00:00 UTC 2009

Novel breast cancer metastasis-associated proteins.

Journal of proteome research

Ho J,Kong JW,Choong LY,Loh MC,Toy W,Chong PK,Wong CH,Wong CY,Shah N,Lim YP

Sun Feb 01 00:00:00 UTC 2009

Novel breast cancer metastasis-associated proteins.

Journal of proteome research

Ho J,Kong JW,Choong LY,Loh MC,Toy W,Chong PK,Wong CH,Wong CY,Shah N,Lim YP

Sun Feb 01 00:00:00 UTC 2009

Novel breast cancer metastasis-associated proteins.

Journal of proteome research

Ho J,Kong JW,Choong LY,Loh MC,Toy W,Chong PK,Wong CH,Wong CY,Shah N,Lim YP

Sun Feb 01 00:00:00 UTC 2009

Bioinformatics

Protein Aliases: 100 kDa coactivator; EBNA-2 co-activator (100kD); EBNA2 coactivator p100; p100 co-activator; p100 EBNA2 co-activator; SND1-BRAF fusion; staphylococcal nuclease domain containing 1; Staphylococcal nuclease domain-containing protein 1; testis tissue sperm-binding protein Li 82P; Tudor domain-containing protein 11; Tudor-SN; TudorSN

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Gene Aliases: p100; SND1; TDRD11

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UniProt ID: (Human) Q7KZF4

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Entrez Gene ID: (Human) 27044

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transcription cofactor activity nuclease activity protein binding poly(A) RNA binding cadherin binding involved in cell-cell adhesion

osteoblast differentiation transcription, DNA-templated regulation of transcription, DNA-templated viral process gene silencing by RNA nucleic acid phosphodiester bond hydrolysis cell-cell adhesion

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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