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Invitrogen
SND1 Polyclonal Antibody
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SND1 Antibody (PA5-40124) in WB
SND1 Polyclonal Antibody detects SND1 protein by western blot analysis. Various whole cell extracts (30 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with SND1 Polyclonal Antibody (Product # PA5-40124) diluted at a dilution of 1:1,000.
Product Details
PA5-40124
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human SND1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.74 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2607118
Product Specific Information
Recommended positive controls: 293T and HepG2 cells.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (89%), Xenopus laevis (93%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activator of EBNA-2. It also interacts with EAV, NSP1, GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 100 kDa coactivator; EBNA-2 co-activator (100kD); EBNA2 coactivator p100; p100 co-activator; p100 EBNA2 co-activator; SND1-BRAF fusion; staphylococcal nuclease domain containing 1; Staphylococcal nuclease domain-containing protein 1; testis tissue sperm-binding protein Li 82P; Tudor domain-containing protein 11; Tudor-SN; TudorSN
Gene Aliases: p100; SND1; TDRD11
UniProt ID: (Human) Q7KZF4
Entrez Gene ID: (Human) 27044
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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