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Invitrogen
SNIP Polyclonal Antibody
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Product Details
PA5-52676
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SNIP. Recombinant protein control fragment (Product #RP-90631).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2647679
Product Specific Information
Immunogen sequence: NDLEKSVEKI QRDVSHNHRL VPGPELEEKA LVLKQLGETL TELKAHFPGL QSKMRVVLRV EVEAVKFLKE EPQRLDGLLK RCRGVTDTLA QIRR
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 98%.
Target Information
Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: P130Cas-associated protein; p140Cap; SNAP-25-interacting protein; SNAP25-interacting protein; SNIP; SRC kinase signaling inhibitor 1
Gene Aliases: KIAA1684; P140; SNIP; SRCIN1
UniProt ID: (Human) Q9C0H9
Entrez Gene ID: (Human) 80725
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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