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Positive Control: A549, H1299
Predicted Reactivity: Mouse (86%), Rat (86%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Syntrophin gamma 2 encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G2SYN; Gamma-2-syntrophin; gamma2-syntrophin; MGC133174; SYN5; syntrophin; syntrophin 5; syntrophin, gamma 2; Syntrophin-5
Gene Aliases: G2SYN; SNTG2; SYN5
UniProt ID: (Human) Q9NY99
Entrez Gene ID: (Human) 54221
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