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Invitrogen
SNURF Polyclonal Antibody
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Product Details
PA5-66794
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human SNURF. Recombinant protein control fragment (Product #RP-107452).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2665283
Product Specific Information
Immunogen sequence: LRRTTEQHVPE VEVQVKRRRT ASLSNQECQL YPRRS
Highest antigen sequence identity to the following orthologs - mouse 97%, rat 94%.
Target Information
SNURF is a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame of its gene is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Sm protein D; Sm protein N; Sm-D; Sm-N; Small nuclear ribonucleoprotein-associated protein N; snRNP-N; SNRPN upstream reading frame protein; Tissue-specific-splicing protein
Gene Aliases: HCERN3; SMN; SNRPN; SNURF
UniProt ID: (Human) Q9Y675
Entrez Gene ID: (Human) 8926
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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