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Invitrogen
SON Polyclonal Antibody
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FIGURE: 1 / 1
SON Antibody (PA5-95740) in WB
Western blot analysis of SON in extracts of various cell lines. Samples were incubated with SON Polyclonal antibody (Product # PA5-95740) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 8 min.
Product Details
PA5-95740
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 850-950 of human SON (NP_0012783401)
Conjugate
Form
Liquid
Concentration
1.18 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2807542
Product Specific Information
Positive Samples: LO2, HeLa
Immunogen sequence: TMDSQMLATS SMDSQMLASG TMDSQMLASG TMDAQMLASG TMDAQMLASS TQDSAMLGSK SPDPYRLAQD PYRLAQDPYR LGHDPYRLGH DAYRLGQDPY R
Target Information
The protein encoded by this gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and the oncoprotein MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing. Several transcript variants encoding different isoforms have been described for this gene, but the full-length nature of only two of them has been determined. [provided by RefSeq].
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BASS1; Bax antagonist selected in Saccharomyces 1; Negative regulatory element-binding protein; NRE-binding protein; Protein DBP-5; Protein SON; SON3
Gene Aliases: BASS1; C21orf50; DBP-5; DBP5; HSPC310; HSPC312; KIAA1019; NREBP; SON; SON3
UniProt ID: (Human) P18583
Entrez Gene ID: (Human) 6651
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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