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Proteintech
SOX12 Polyclonal Antibody
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Product Details
23939-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SOX12 Fusion Protein Ag21043 (1-315 aa encoded by BC067361)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MVQQRGARA KRDGGPPPPG PGPAEEGARE PGWCKTPSGH IKRPMNAFMV WSQHERRKIM DQWPDMHNAE ISKRLGRRWQ LLQDSEKIPF VREAERLRLK HMADYPDYKY RPRKKSKGAP AKARPRPPGG SGGGSRLKPG PQLPGRGGRR AAGGPLGGGA AAPEDDDEDD DEELLEVRLV ETPGRELWRM VPAGRAARGQ AERAQGPSGE GAAAAAAASP TPSEDEEPEE EEEEAAAAEE GEEETVASGE ESLGFLSRLP PGPAGLDCSA LDRDPDLQPP SGTSHFEFPD YCTPEVTEMI AGDWRPSSIA DLVFTY (1-315 aa encoded by B C067361)
Target Information
Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Protein SOX-22; SOX-22 protein; SRY (sex determining region Y)-box 12; SRY box 12; SRY-box containing gene 12; SRY-related HMG-box gene 22; Transcription factor SOX-12
Gene Aliases: 2010205A02Rik; Sox-12; SOX12; SOX22
UniProt ID: (Human) O15370, (Mouse) Q04890
Entrez Gene ID: (Human) 6666, (Mouse) 20667
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
spinal cord development
positive regulation of transcription from RNA polymerase II promoter
protein-DNA complex assembly
regulation of transcription from RNA polymerase II promoter
cell fate commitment
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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