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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SOX21 Antibodies

          Proteintech

          SOX21 Polyclonal Antibody

          2 References
          View all (4) SOX21 antibodies

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          Datasheet
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          Cite SOX21 Polyclonal Antibody

          • Antibody Testing Data (4)
          SOX21 Antibody in Western Blot (WB)
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          SOX21 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          SOX21 Antibody (55052-1-AP) in WB

          Mouse embryo tissue were subjected to SDS PAGE followed by western blot with 55052-1-AP ( SOX21 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SOX21 Antibody in Western Blot (WB)
          SOX21 Antibody in Western Blot (WB)
          SOX21 Antibody in Western Blot (WB)
          SOX21 Antibody in Western Blot (WB)

          Product Details

          55052-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:200-1:1,000
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Human, Mouse

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Peptide

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.53 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          0.1M sodium bicarbonate/0.1M glycine, pH 7.3, with 50% glycerol, 0.1M glycine

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Target Information

          The SOX gene family is defined by the Sry-related HMG box domain that mediates sequence-specific DNA binding. A variety of functions are associated with the SOX proteins during development. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. SOX21 may play a role as an activator of transcription of OPRM1. Overexpression of SOX21 can cause an up-regulation of the OPRM1 distal promoter in mor-expressing neuronal cells.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: DNA-binding protein SOX21; HMG-box protein SOX21; SOX-A; SOX25SOX-A; SRY (sex determining region Y)-box 21; SRY box 21; SRY-box containing gene 21; Transcription factor SOX-21

          View more View less

          Gene Aliases: SOX21; SOX25; SOXA

          View more View less

          UniProt ID: (Human) Q9Y651, (Mouse) Q811W0

          View more View less

          Entrez Gene ID: (Human) 11166, (Mouse) 223227

          View more View less

          Function(s)
          RNA polymerase II transcription factor activity, sequence-specific DNA binding DNA binding transcription factor activity, sequence-specific DNA binding
          Process(es)
          hair follicle development transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter stem cell differentiation hair cycle skin development negative regulation of neuron differentiation
          It has to be done as per old AB suggested Products section.
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