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Invitrogen
SOX3 Monoclonal Antibody (CL4725)
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Product Details
MA5-24710
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
CL4725
Immunogen
Recombinant Human SOX3
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2662853
Product Specific Information
Immunogen sequence: RENSSGARSPR VPADLARSIL ISLPFPPDSL AHRPPSSAPT ESQGLFTVAA PAPGAPSPPA TLAHLLPAPA MYSLLETELK NPVGTPTQAA GTGGPAAPGG AGKSSA
Binds to an epitope located within the peptide sequence LISLPFPPDS as determined by overlapping synthetic peptides.
Highest antigen sequence identity to the following orthologs - mouse 82%, rat 31%.
Target Information
This gene encodes a member of the SOX family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SRY (sex determining region Y)-box 3; SRY box 3; Transcription factor SOX-3
Gene Aliases: GHDX; MRGH; PHP; PHPX; SOX3; SOXB
UniProt ID: (Human) P41225
Entrez Gene ID: (Human) 6658
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
central nervous system development
sensory organ development
sex determination
hypothalamus development
pituitary gland development
negative regulation of neuron differentiation
neuron development
face development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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