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SOX5 Polyclonal Antibody

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SOX5 Antibody (13216-1-AP) in WB

SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 13216-1-AP (SOX5 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Product Details

13216-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SOX5 Fusion Protein Ag4092 (2-376 aa encoded by BC029220)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.21 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: DEVAQPLNL SAKPKTSDGK SPTSPTSPHM PALRINSGAG PLKASVPAAL ASPSARVSTI GYLNDHDAVT KAIQEARQMK EQLRREQQVL DGKVAVVNSL GLNNCRTEKE KTTLESLTQQ LAVKQNEEGK FSHAMMDFNL SGDSDGSAGV SESRIYRESR GRGSNEPHIK RPMNAFMVWA KDERRKILQA FPDMHNSNIS KILGSRWKAM TNLEKQPYYE EQARLSKQHL EKYPDYKYKP RPKRTCLVDG KKLRIGEYKA IMRNRRQEMR QYFNVGQQAQ IPIATAGVVY PGAIAMAGMP SPHLPSEHSS VSSSPEPGMP VIQSTYGVKG EEPHIKEEIQ AEDINGEIYD EYDEEEDDPD VDYGSDSENH IAGQAN (2-376 aa encoded by B C029220)

Target Information

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Transcriptomics, molecular docking, and cross-resistance profiling of nobiletin in cancer cells and synergistic interaction with doxorubicin upon SOX5 transfection.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Adham AN,Abdelfatah S,Naqishbandi A,Sugimoto Y,Fleischer E,Efferth T

Wed Jun 01 00:00:00 UTC 2022

Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways.

Pharmacological research

Cai J,Liang J,Zhang Y,Shen L,Lin H,Hu T,Zhan S,Xie M,Liang S,Xian M,Wang S

Wed Jun 01 00:00:00 UTC 2022

High expression levels and localization of Sox5 in dilated cardiomyopathy.

Molecular medicine reports

Liu Y,Jiang B,Cao Y,Chen W,Yin L,Xu Y,Qiu Z

Sat Aug 01 00:00:00 UTC 2020

Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.

Laboratory investigation; a journal of technical methods and pathology

Feng M,Fang F,Fang T,Jiao H,You S,Wang X,Zhao W

Sun Nov 01 00:00:00 UTC 2020

Apatinib inhibits glycolysis by suppressing the VEGFR2/AKT1/SOX5/GLUT4 signaling pathway in ovarian cancer cells.

Cellular oncology (Dordrecht, Netherlands)

Chen L,Cheng X,Tu W,Qi Z,Li H,Liu F,Yang Y,Zhang Z,Wang Z

Tue Oct 01 00:00:00 UTC 2019

Apatinib inhibits glycolysis by suppressing the VEGFR2/AKT1/SOX5/GLUT4 signaling pathway in ovarian cancer cells.

Cellular oncology (Dordrecht, Netherlands)

Chen L,Cheng X,Tu W,Qi Z,Li H,Liu F,Yang Y,Zhang Z,Wang Z

Tue Oct 01 00:00:00 UTC 2019

Expression profiles of Sox transcription factors within the postnatal rodent testes.

Molecular and cellular biochemistry

Roumaud P,Haché J,Martin LJ

Mon Oct 01 00:00:00 UTC 2018

Expression profiles of Sox transcription factors within the postnatal rodent testes.

Molecular and cellular biochemistry

Roumaud P,Haché J,Martin LJ

Mon Oct 01 00:00:00 UTC 2018

VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.

Nature communications

Miyamoto Y,Torii T,Tanoue A,Yamauchi J

Wed Nov 23 00:00:00 UTC 2016

VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.

Nature communications

Miyamoto Y,Torii T,Tanoue A,Yamauchi J

Wed Nov 23 00:00:00 UTC 2016

Expressions of Sox9, Sox5, and Sox13 transcription factors in mice testis during postnatal development.

Molecular and cellular biochemistry

Daigle M,Roumaud P,Martin LJ

Tue Sep 01 00:00:00 UTC 2015

Expressions of Sox9, Sox5, and Sox13 transcription factors in mice testis during postnatal development.

Molecular and cellular biochemistry

Daigle M,Roumaud P,Martin LJ

Tue Sep 01 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: MGC35153; Sox5-BLM isoform; SRY (sex determining region Y)-box 5; SRY box 5; SRY-box containing gene 5; SRY-box containing gene 5-like 1; Transcription factor SOX-5

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Gene Aliases: A730017D01Rik; AI528773; L-SOX5; L-SOX5B; L-SOX5F; LAMSHF; Sox-5; SOX5; Sox5l1

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UniProt ID: (Human) P35711, (Rat) F1M8W4, (Mouse) P35710

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Entrez Gene ID: (Human) 6660, (Rat) 140587, (Mouse) 20678

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Function(s)

DNA binding transcription factor activity, sequence-specific DNA binding protein binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription regulatory region DNA binding protein heterodimerization activity

Process(es)

regulation of transcription, DNA-templated transcription from RNA polymerase II promoter positive regulation of chondrocyte differentiation asymmetric neuroblast division positive regulation of cartilage development cellular response to transforming growth factor beta stimulus positive regulation of mesenchymal stem cell differentiation in utero embryonic development central nervous system neuron differentiation cell fate commitment negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter oligodendrocyte differentiation cartilage development regulation of timing of neuron differentiation transcription, DNA-templated

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SOX5 Polyclonal Antibody

SOX5 Antibody (13216-1-AP) in WB

Product Details

13216-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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