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Invitrogen
SOX5 Polyclonal Antibody
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Product Details
PA5-104343
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SOX5(Accession P35711), corresponding to amino acid residues M90-A140.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853653
Product Specific Information
Antibody detects endogenous levels of total SOX5.
Target Information
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC35153; Sox5-BLM isoform; SRY (sex determining region Y)-box 5; SRY box 5; SRY-box containing gene 5; SRY-box containing gene 5-like 1; Transcription factor SOX-5
Gene Aliases: A730017D01Rik; AI528773; L-SOX5; L-SOX5B; L-SOX5F; LAMSHF; Sox-5; SOX5; Sox5l1
UniProt ID: (Human) P35711, (Rat) F1M8W4, (Mouse) P35710
Entrez Gene ID: (Human) 6660, (Rat) 140587, (Mouse) 20678
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of chondrocyte differentiation
asymmetric neuroblast division
positive regulation of cartilage development
cellular response to transforming growth factor beta stimulus
positive regulation of mesenchymal stem cell differentiation
in utero embryonic development
central nervous system neuron differentiation
cell fate commitment
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
oligodendrocyte differentiation
cartilage development
regulation of timing of neuron differentiation
transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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