Proteintech

SOX6 Polyclonal Antibody

FIGURE: 1 / 1

SOX6 Antibody (14010-1-AP) in WB

Jurkat cells were subjected to SDS PAGE followed by western blot with 14010-1-AP (SOX6 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Product Details

14010-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 5 publications 5 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SOX6 Fusion Protein Ag5111 (272-828 aa encoded by BC047064)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.23 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: FPHDQRTLA AAAAAQQGFL FPPGITYKPG DNYPVQFIPS TMAAAAASGL SPLQLQKGHV SHPQINQRLK GLSDRFGRNL DTFEHGGGHS YNHKQIEQLY AAQLASMQVS PGAKMPSTPQ PPNTAGTVSP TGIKNEKRGT SPVTQVKDEA AAQPLNLSSR PKTAEPVKSP TSPTQNLFPA SKTSPVNLPN KSSIPSPIGG SLGRGSSLDI LSSLNSPALF GDQDTVMKAI QEARKMREQI QREQQQQQPH GVDGKLSSIN NMGLNSCRNE KERTRFENLG PQLTGKSNED GKLGPGVIDL TRPEDAEGSK AMNGSAAKLQ QYYCWPTGGA TVAEARVYRD ARGRASSEPH IKRPMNAFMV WAKDERRKIL QAFPDMHNSN ISKILGSRWK SMSNQEKQPY YEEQARLSKI HLEKYPNYKY KPRPKRTCIV DGKKLRIGEY KQLMRSRRQE MRQFFTVGQQ PQIPITTGTG VVYPGAITMA TTTPSPQMTS DCSSTSASPE PSLPVIQSTY GMKTDGGSLA GNEMINGEDE MEMYDDYEDD PKSDYSSENE APEAVSAN (272-828 aa encoded by BC047064)

Target Information

Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

CircHOMER1 aggravates oxidative stress, inflammation and extracellular matrix deposition in high glucose-induced human mesangial cells.

Nephrology (Carlton, Vic.)

Shu S,Xu Z,Lu H,Li Z,Zhang Y

Thu Dec 01 00:00:00 UTC 2022

Reversing a model of Parkinson's disease with in situ converted nigral neurons.

Nature

Qian H,Kang X,Hu J,Zhang D,Liang Z,Meng F,Zhang X,Xue Y,Maimon R,Dowdy SF,Devaraj NK,Zhou Z,Mobley WC,Cleveland DW,Fu XD

Mon Jun 01 00:00:00 UTC 2020

miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6.

International journal of molecular medicine

Jiang ZH,Tang YZ,Song HN,Yang M,Li B,Ni CL

Wed Jan 01 00:00:00 UTC 2020

MicroRNA-135a-5p promotes neuronal differentiation of pluripotent embryonal carcinoma cells by repressing Sox6/CD44 pathway.

Biochemical and biophysical research communications

Li W,Fang J,Shen J,Liu X,Hou J,Zhu Y,Ma X

Tue Feb 05 00:00:00 UTC 2019

MicroRNA-135a-5p promotes neuronal differentiation of pluripotent embryonal carcinoma cells by repressing Sox6/CD44 pathway.

Biochemical and biophysical research communications

Li W,Fang J,Shen J,Liu X,Hou J,Zhu Y,Ma X

Tue Feb 05 00:00:00 UTC 2019

LncRNA Riken-201 and Riken-203 modulates neural development by regulating the Sox6 through sequestering miRNAs.

Cell proliferation

Zhang L,Xue Z,Yan J,Wang J,Liu Q,Jiang H

Wed May 01 00:00:00 UTC 2019

LncRNA Riken-201 and Riken-203 modulates neural development by regulating the Sox6 through sequestering miRNAs.

Cell proliferation

Zhang L,Xue Z,Yan J,Wang J,Liu Q,Jiang H

Wed May 01 00:00:00 UTC 2019

VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.

Nature communications

Miyamoto Y,Torii T,Tanoue A,Yamauchi J

Wed Nov 23 00:00:00 UTC 2016

VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.

Nature communications

Miyamoto Y,Torii T,Tanoue A,Yamauchi J

Wed Nov 23 00:00:00 UTC 2016

Bioinformatics

Protein Aliases: SOX-LZ; SRY (sex determining region Y)-box 6; SRY box 6; SRY-box containing gene 6; Transcription factor SOX-6

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Gene Aliases: AI987981; HSSOX6; Sox-6; SOX-LZ; SOX6; SOXD

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UniProt ID: (Human) P35712, (Rat) A0A0G2JTZ2, (Mouse) P40645

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Entrez Gene ID: (Human) 55553, (Rat) 293165, (Mouse) 20679

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Function(s)

DNA binding transcription factor activity, sequence-specific DNA binding protein binding sequence-specific DNA binding transcription regulatory region DNA binding protein heterodimerization activity

Process(es)

negative regulation of transcription from RNA polymerase II promoter cell morphogenesis in utero embryonic development regulation of transcription, DNA-templated post-embryonic development regulation of gene expression gene silencing oligodendrocyte cell fate specification hemopoiesis erythrocyte differentiation positive regulation of chondrocyte differentiation muscle cell differentiation cell fate commitment negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter astrocyte differentiation oligodendrocyte differentiation erythrocyte development cartilage development cardiac muscle cell differentiation positive regulation of cartilage development cellular response to transforming growth factor beta stimulus positive regulation of mesenchymal stem cell differentiation transcription, DNA-templated multicellular organism development muscle organ development negative regulation of cardiac muscle cell differentiation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SOX6 Polyclonal Antibody

SOX6 Antibody (14010-1-AP) in WB

Product Details

14010-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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