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Immunogen sequence: QQQVVQIPQ QALRVVQAAS ATLPTVPQKP SQNFQIQAAE PTPTQVYIRT PSGEVQTVLV QDSPPATAAA TSNTTCSSPA SRAPHLSGTS KKHSAAILRK ERPLPKIAPA GSIISLNAAQ LAAAAQAMQT ININGVQVQG VPVTITNTGG QQQLTVQNVS GNNLTISGLS PTQIQLQMEQ ALAGETQPGE KRRRMACTCP NCKDGEKRSG EQGKKKHVCH IPDCGKTFRK TSLLRAHVRL HTGERPFVCN WFFCGKRFTR SDELQRHART HTGDKRFECA QCQKRFMRSD HLTKHYKTHL VTKNL (303-606 aa encoded by BC016680)
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Trans-acting transcription factor 2; Transcription factor Sp2
Gene Aliases: KIAA0048; SP2
UniProt ID: (Human) Q02086
Entrez Gene ID: (Human) 6668, (Rat) 303499
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