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FIGURE: 1 / 1
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.
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Protein Aliases: Trans-acting transcription factor 2; Transcription factor Sp2
Gene Aliases: 4930480I16Rik; KIAA0048; mKIAA0048; SP2
UniProt ID: (Human) Q02086, (Mouse) Q9D2H6
Entrez Gene ID: (Human) 6668, (Mouse) 78912, (Rat) 303499
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