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          • Primary Antibodies ›
          • SPAG4 Antibodies

          Invitrogen

          SPAG4 Polyclonal Antibody

          View all (8) SPAG4 antibodies

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          Cite SPAG4 Polyclonal Antibody

          • Antibody Testing Data (1)
          SPAG4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          SPAG4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 1

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          SPAG4 Antibody (PA5-63985) in IHC (P)

          Immunohistochemical analysis of SPAG4 in human testis using SPAG4 Polyclonal Antibody (Product # PA5-63985) shows moderate cytoplasmic positivity in spermatids. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SPAG4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Product Details

          PA5-63985

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human SPAG4. Recombinant protein control fragment (Product #RP-103423).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2647778

          Product Specific Information

          Immunogen sequence: LSDITLQHPP PSVEHTGGAN SAPRDFAVFG LQVYDETEVS LGKFTFDVEK SEIQTFHLQN DPPAAFPKVK IQILSNWGH

          Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 86%.

          Target Information

          The mammalian sperm flagellum contains two cytoskeletal structures associated with the axoneme: the outer dense fibers surrounding the axoneme in the midpiece and principal piece and the fibrous sheath surrounding the outer dense fibers in the principal piece of the tail. Defects in these structures are associated with abnormal tail morphology, reduced sperm motility, and infertility. In the rat, the protein encoded by this gene associates with an outer dense fiber protein via a leucine zipper motif and localizes to the microtubules of the manchette and axoneme during sperm tail development.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: acrosomal protein ACR55; cancer/testis antigen 127; Outer dense fiber-associated protein SPAG4; Sad1 and UNC84 domain containing 4; sperm tail protein; Sperm-associated antigen 4 protein; SUN domain-containing protein 4

          View more View less

          Gene Aliases: CT127; SPAG4; SUN4

          View more View less

          UniProt ID: (Human) Q9NPE6

          View more View less

          Entrez Gene ID: (Human) 6676

          View more View less

          Function(s)
          structural molecule activity protein binding
          Process(es)
          nuclear envelope organization spermatogenesis cytoskeletal anchoring at nuclear membrane
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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