Proteintech

SPATA7 Polyclonal Antibody

SPATA7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 19

SPATA7 Antibody (12020-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human testis tissue slide using 12020-1-AP ( SPATA7 Antibody) at dilution of 1:50 (under 40x lens).

SPATA7 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

12020-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 3 publications 3 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SPATA7 Fusion Protein Ag2649 (120-468 aa encoded by BC008656)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

The antibody can recognize all 3 isoforms of SPATA7.

Immunogen sequence: SFLSQYRYY TPAKRKKDFT DQRIEAETQT ELSFKSELGT AETKNMTDSE MNIKQASNCV TYDAKEKIAP LPLEGHDSTW DEIKDDALQH SSPRAMCQYS LKPPSTRKIY SDEEELLYLS FIEDVTDEIL KLGLFSNRFL ERLFERHIKQ NKHLEEEKMR HLLHVLKVDL GCTSEENSVK QNDVDMLNVF DFEKAGNSEP NELKNESEVT IQQERQQYQK ALDMLLSAPK DENEIFPSPT EFFMPIYKSK HSEGVIIQQV NDETNLETST LDENHPSISD SLTDRETSVN VIEGDSDPEK VEISNGLCGL NTSPSQSVQF SSVKGDNNHD MELSTLKIME MSIEDCPLDV (120-468 aa encoded by BC008656)

Target Information

The function of the SPATA7 protein remains unknown.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Conditional loss of Spata7 in photoreceptors causes progressive retinal degeneration in mice.

Experimental eye research

Eblimit A,Agrawal SA,Thomas K,Anastassov IA,Abulikemu T,Moayedi Y,Mardon G,Chen R

Mon Jan 01 00:00:00 UTC 2018

Conditional loss of Spata7 in photoreceptors causes progressive retinal degeneration in mice.

Experimental eye research

Eblimit A,Agrawal SA,Thomas K,Anastassov IA,Abulikemu T,Moayedi Y,Mardon G,Chen R

Mon Jan 01 00:00:00 UTC 2018

Spata7 is a retinal ciliopathy gene critical for correct RPGRIP1 localization and protein trafficking in the retina.

Human molecular genetics

Eblimit A,Nguyen TM,Chen Y,Esteve-Rudd J,Zhong H,Letteboer S,Van Reeuwijk J,Simons DL,Ding Q,Wu KM,Li Y,Van Beersum S,Moayedi Y,Xu H,Pickard P,Wang K,Gan L,Wu SM,Williams DS,Mardon G,Roepman R,Chen R

Sun Mar 15 00:00:00 UTC 2015

Spata7 is a retinal ciliopathy gene critical for correct RPGRIP1 localization and protein trafficking in the retina.

Human molecular genetics

Eblimit A,Nguyen TM,Chen Y,Esteve-Rudd J,Zhong H,Letteboer S,Van Reeuwijk J,Simons DL,Ding Q,Wu KM,Li Y,Van Beersum S,Moayedi Y,Xu H,Pickard P,Wang K,Gan L,Wu SM,Williams DS,Mardon G,Roepman R,Chen R

Sun Mar 15 00:00:00 UTC 2015

AAV8(Y733F)-mediated gene therapy in a Spata7 knockout mouse model of Leber congenital amaurosis and retinitis pigmentosa.

Gene therapy

Zhong H,Eblimit A,Moayedi Y,Boye SL,Chiodo VA,Chen Y,Li Y,Nichols RM,Hauswirth WW,Chen R,Mardon G

Sat Aug 01 00:00:00 UTC 2015

AAV8(Y733F)-mediated gene therapy in a Spata7 knockout mouse model of Leber congenital amaurosis and retinitis pigmentosa.

Gene therapy

Zhong H,Eblimit A,Moayedi Y,Boye SL,Chiodo VA,Chen Y,Li Y,Nichols RM,Hauswirth WW,Chen R,Mardon G

Sat Aug 01 00:00:00 UTC 2015

Mutations in SPATA7 cause Leber congenital amaurosis and juvenile retinitis pigmentosa.

American journal of human genetics

Wang H,den Hollander AI,Moayedi Y,Abulimiti A,Li Y,Collin RW,Hoyng CB,Lopez I,Abboud EB,Al-Rajhi AA,Bray M,Lewis RA,Lupski JR,Mardon G,Koenekoop RK,Chen R

Sun Mar 01 00:00:00 UTC 2009

Mutations in SPATA7 cause Leber congenital amaurosis and juvenile retinitis pigmentosa.

American journal of human genetics

Wang H,den Hollander AI,Moayedi Y,Abulimiti A,Li Y,Collin RW,Hoyng CB,Lopez I,Abboud EB,Al-Rajhi AA,Bray M,Lewis RA,Lupski JR,Mardon G,Koenekoop RK,Chen R

Sun Mar 01 00:00:00 UTC 2009

Mutations in SPATA7 cause Leber congenital amaurosis and juvenile retinitis pigmentosa.

American journal of human genetics

Wang H,den Hollander AI,Moayedi Y,Abulimiti A,Li Y,Collin RW,Hoyng CB,Lopez I,Abboud EB,Al-Rajhi AA,Bray M,Lewis RA,Lupski JR,Mardon G,Koenekoop RK,Chen R

Sun Mar 01 00:00:00 UTC 2009

Bioinformatics

Protein Aliases: epididymis secretory protein Li 296; fertility related protein WMP1; fertility-related protein WMP1; HSD-3.1; sperm DNA no.3; Spermatogenesis-associated protein 7; Spermatogenesis-associated protein 7 homolog; Spermatogenesis-associated protein HSD3

View more View less

Gene Aliases: AI661438; B230306G18Rik; HEL-S-296; HSD-3.1; HSD3; LCA3; RSD-3; SPATA7; Wmp1

View more View less

UniProt ID: (Human) Q9P0W8, (Mouse) Q80VP2

View more View less

Entrez Gene ID: (Human) 55812, (Mouse) 104871, (Rat) 192225

View more View less

Function(s)

protein binding molecular_function

Process(es)

visual perception photoreceptor cell maintenance response to stimulus protein localization to photoreceptor outer segment protein localization to photoreceptor connecting cilium spermatogenesis

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

SPATA7 Polyclonal Antibody

SPATA7 Antibody (12020-1-AP) in IHC (P)

Product Details

12020-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!