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Immunogen sequence: LHLRNELRDM RAQLGINEDH SEGDEKSEKE TIMAHQPTDV ESTLLQLQEQ NTAIREELNQ LKNENRMLKD RLNALGFSLE QRLDNSEKLF GYQSLSPEIT PGNQSDGGGT LTSSVEGSAP GSVEDLLSQD ENTLMDHQHS NSMDNLDSEC SEVYQPLTSS DDALDAPSSS ESEGIPSIER SRKGSSGNAS EVSVACLTER IHQMEENQHS TSEELQATLQ ELADLQQITQ ELNSENERLG EEKVILMESL CQQSDKLEHF SRQIEYFRSL LDEHHISYVI DEDVKSGRYM ELEQRYMDLA E; Positive Samples: LO2, HeLa, A375; Cellular Location: Cell junction, Cytoplasm, cytoskeleton, gap junction, spindle
This gene encodes a protein that is leucine-rich and is thought to play a role in regulating the interaction of the cytoskeleton with a variety of cellular processes. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. Transcripts ranging in size from 4. 8 to 7. 0 kb which result from alternative polyadenylation have been reported for this gene.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cytokinesis and spindle organization A; Cytospin-A; Renal carcinoma antigen NY-REN-22; SPECC1-like; SPECC1-like protein; Sperm antigen with calponin homology and coiled-coil domains 1-like
Gene Aliases: CYTSA; GBBB2; KIAA0376; OBLFC1; SPECC1L
UniProt ID: (Human) Q69YQ0
Entrez Gene ID: (Human) 23384
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