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Invitrogen
SPG21 Polyclonal Antibody
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Product Details
PA5-65268
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human SPG21. Recombinant protein control fragment (Product #RP-104718).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2664995
Product Specific Information
Immunogen sequence: AKEEMYKLYPN ARRAHLKTGG NFPYLCRSAE VNLYVQIHLL QFHGTKYAAI DPSMVSAEEL EVQKGSLGIS QEEQ
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 92%.
Target Information
The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acid cluster protein 33; Maspardin; Spastic paraplegia 21 autosomal recessive Mast syndrome protein; Spastic paraplegia 21 protein
Gene Aliases: ACP33; BM-019; GL010; MAST; SPG21
UniProt ID: (Human) Q9NZD8
Entrez Gene ID: (Human) 51324
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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