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Invitrogen
SPIDR Polyclonal Antibody
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Product Details
PA5-65304
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human SPIDR. Recombinant protein control fragment (Product #RP-104738).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2663280
Product Specific Information
Immunogen sequence: PALCYILTAHP NLGQIDIIDE DPIYKLYQPP VTRCLRDILQ MNDLGTRCSF YATVIYQKPQ LKSLLLLEQR EIWLLVTDVT LQTK
Highest antigen sequence identity to the following orthologs - mouse 72%, rat 67%.
Target Information
Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR). Serves as a scaffolding protein that helps to promote the recruitment of DNA-processing enzymes like the helicase BLM and recombinase RAD51 to site of DNA damage, and hence contributes to maintain genomic integrity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA repair-scaffolding protein; k0146; Scaffolding protein involved in DNA repair
Gene Aliases: KIAA0146; SPIDR
UniProt ID: (Human) Q14159
Entrez Gene ID: (Human) 23514
double-strand break repair via homologous recombination
cellular response to DNA damage stimulus
regulation of double-strand break repair via homologous recombination
positive regulation of protein complex assembly
regulation of establishment of protein localization to chromosome
cellular response to ionizing radiation
cellular response to hydroxyurea
cellular response to camptothecin
positive regulation of double-strand break repair
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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