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Product Details
H00006692-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SPINT1 (NP_001027539.1, 1 a.a. approximately 513 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAPARTMARA RLAPAGIPAV ALWLLCTLGL QGTQAGPPPA PPGLPAGADC LNSFTAGVPG FVLDTNASVS NGATFLESPT VRRGWDCVRA CCTTQNCNLA LVELQPDRGE DAIAACFLIN CLYEQNFVCK FAPREGFINY LTREVYRSYR QLRTQGFGGS GIPKAWAGID LKVQPQEPLV LKDVENTDWR LLRGDTDVRV ERKDPNQVEL WGLKEGTYLF QLTVTSSDHP EDTANVTVTV LSTKQTEDYC LASNKVGRCR GSFPRWYYDP TEQICKSFVY GGCLGNKNNY LREEECILAC RGVQGPSMER RHPVCSGTCQ PTQFRCSNGC CIDSFLECDD TPNCPDASDE AACEKYTSGF DELQRIHFPS DKGHCVDLPD TGLCKESIPR WYYNPFSEHC ARFTYGGCYG NKNNFEEEQQ CLESCRGISK KDVFGLRREI PIPSTGSVEM AVAVFLVICI VVVVAILGYC FFKNQRKDFH GHHHHPPPTP ASSTVSTTED TEHLVYNHTT RPL
Target Information
The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HAI-1; Hepatocyte growth factor activator inhibitor type 1; Kunitz-type protease inhibitor 1; serine protease inhibitor, Kunitz type 1
Gene Aliases: HAI; HAI1; MANSC2; SPINT1; UNQ223/PRO256
UniProt ID: (Human) O43278
Entrez Gene ID: (Human) 6692
neural tube closure
negative regulation of endopeptidase activity
extracellular matrix organization
positive regulation of glial cell differentiation
branching involved in labyrinthine layer morphogenesis
placenta blood vessel development
cellular response to BMP stimulus
negative regulation of neural precursor cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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