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Abnova
SPIRE1 Monoclonal Antibody (4C5)
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Product Details
H00056907-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
4C5
Immunogen
SPIRE1 (NP_064533, 482 a.a. approximately 583 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: SEKPSTAHHR PLRSIARFSS KSKSMDKSDE ELQFPKELME DWSTMEVCVD CKKFISEIIS SSRRSLVLAN KRARLKRKTQ SFYMSSPGPS EYCPSERTIS EI
Target Information
Acts as a actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein spire homolog 1; Spir-1; spire actin nucleation factor 1; spire family actin nucleation factor 1; spire homolog 1; spire-type actin nucleation factor 1; SPIRE1
Gene Aliases: KIAA1135; Spir-1; SPIR1; SPIRE1
UniProt ID: (Human) Q08AE8
Entrez Gene ID: (Human) 56907
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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