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Invitrogen
SPON2 Polyclonal Antibody
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Product Details
PA5-37919
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-RTRYVRVQPANNGSP, from the internal region near the C-terminus of SPON2 (aa301-315)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2554526
Product Specific Information
This antibody is predicted to react with mouse, rat and dog based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
Target Information
Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens. Binds bacterial lipopolysaccharide (LPS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Differentially expressed in cancerous and non-cancerous lung cells 1; DIL-1; DKFZp686G21139; F-spondin; FLJ16313; FLJ22401; FLJ34460; Mindin; spondin 2, extracellular matrix protein; Spondin-2
Gene Aliases: 2310045I24Rik; AI504350; DIL-1; DIL1; M-SPONDIN; MINDIN; Mspondin; SPON2; UNQ435/PRO866
UniProt ID: (Human) Q9BUD6, (Mouse) Q8BMS2, (Rat) Q9WV75
Entrez Gene ID: (Human) 10417, (Mouse) 100689, (Rat) 171569
mast cell mediated immunity
cell adhesion
axon guidance
opsonization
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
induction of bacterial agglutination
innate immune response
defense response to fungus
defense response to virus
positive regulation of macrophage cytokine production
cellular response to lipopolysaccharide
immune system process
response to lipopolysaccharide
defense response to bacterium
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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