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A suggested positive control is mouse kidney tissue lysate.
PA5-21174 can be used with blocking peptide PEP-1288.
The SPRY domain-containing protein 4 (SPRYD4) is a member of a family of proteins whose sole common characteristic is the presence of a SPRY domain. SPRY domains are structural domains that were first described in the fungal Dictyostelium discoideum tyrosine kinase spore lysis A. In most systems SPRY domains provide binding sites for regulatory proteins or intramolecular binding sites that maintain the structural integrity of a protein. SPRYD4 is ubiquitously expressed and is most abundant in kidney, brain, bladder, thymus and stomach. Little is known of the function of the SPRYD4 protein.
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Protein Aliases: SPRY domain-containing protein 4
Gene Aliases: 4633402N23Rik; AA114801; RGD1306649; SPRYD4
UniProt ID: (Human) Q8WW59, (Rat) Q4FZT8, (Mouse) Q91WK1
Entrez Gene ID: (Human) 283377, (Rat) 288772, (Mouse) 66701
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