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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SPTLC3 Antibodies

          Invitrogen

          SPTLC3 Polyclonal Antibody

          View all (3) SPTLC3 antibodies
          Datasheet
          Protocols
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          Datasheet
          Protocols
          Questions & Answers

          Cite SPTLC3 Polyclonal Antibody

          • Antibody Testing Data (4)
          SPTLC3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          SPTLC3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          SPTLC3 Antibody (PA5-98858) in ICC/IF

          Immunofluorescent analysis of SPTLC3 in HepG2 cells using a SPTLC3 polyclonal antibody (Product # PA5-98858) at a dilution of 1:100. Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L) secondary antibody was used. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SPTLC3 Antibody in Immunocytochemistry (ICC/IF)
          SPTLC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SPTLC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SPTLC3 Antibody in Western Blot (WB)

          Product Details

          PA5-98858

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:5,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          ELISA (ELISA)

          Assay-Dependent
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human Serine palmitoyltransferase 3 protein (1-58AA)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          4.86 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.03% ProClin 300

          Storage conditions

          -20°C or -80°C if preferred

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2813471

          Target Information

          Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, while the SPTLC1-SPTLC3-SPTSSB has the ability to use a broader range of acyl-CoAs without apparent preference.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: LCB 3; LCB2b; Long chain base biosynthesis protein 2b; Long chain base biosynthesis protein 3; Serine palmitoyltransferase 3; serine palmitoyltransferase, long chain base subunit 2-like (aminotransferase 2); serine palmitoyltransferase, long chain base subunit 3; Serine-palmitoyl-CoA transferase 3; Serine-palmityl-CoA transferase 3; SPT 3

          View more View less

          Gene Aliases: C130053K05Rik; C20orf38; dJ718P11; dJ718P11.1; hLCB2b; LCB2B; LCB3; SPT3; SPTLC2L; SPTLC3

          View more View less

          UniProt ID: (Human) Q9NUV7, (Mouse) Q8BG54

          View more View less

          Entrez Gene ID: (Human) 55304, (Mouse) 228677

          View more View less

          Function(s)
          serine C-palmitoyltransferase activity pyridoxal phosphate binding catalytic activity transferase activity transferase activity, transferring acyl groups
          Process(es)
          sphingolipid biosynthetic process sphingoid biosynthetic process lipid metabolic process sphingolipid metabolic process metabolic process biosynthetic process
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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