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Product Details
CL488-67206
Product Specifications
Species Reactivity
Human,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1C9A2
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: SRDGRKVTVI ERDLKEPDRI VGEFLQPGGY HVLKDLGLGD TVEGLDAQVV NGYMIHDQES KSEVQIPYPL SENNQVQSGR AFHHGRFIMS LRKAAMAEPN AKFIEGVVLQ LLEEDDVVMG VQYKDKETGD IKELHAPLTV VADGLFSKFR KSLVSNKVSV SSHFVGFLMK NAPQFKANHA ELILANPSPV LIYQISSSET RVLVDIRGEM PRNLREYMVE KIYPQIPDHL KEPFLEATDN SHLRSMPASF LPPSSVKKRG VLLLGDAYNM RHPLTGGGMT VAFKDIKLWR KLLKGIPDLY DDAAIFEAKK SFYWARKTSH SFVVNILAQA LYELFSATDD SLHQLRKACF LYFKLGGECV AGPVGL
Target Information
SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also post translationally regulated by cholesterol-dependent proteasomal degradation. The MW of SQLE is about 64 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ30795; SE; Squalene epoxidase; Squalene monooxygenase
Gene Aliases: ERG1; SQLE
UniProt ID: (Human) Q14534, (Rat) P52020
Entrez Gene ID: (Pig) 100113409, (Human) 6713, (Rat) 29230
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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