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Invitrogen
SQRDL Polyclonal Antibody
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Product Details
PA5-53549
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SQRDL. Recombinant protein control fragment (Product #RP-89842).
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2647905
Product Specific Information
Immunogen sequence: TSPVADAAGW VDVDKETLQH RRYPNVFGIG DCTNLPTSKT AAAVAAQSGI LDRTISVIMK NQTPTKKYDG YTSCPLVTGY NRVILAEFDY KAEPLETFPF DQSKERLSMY LMKADLMPFL YWNMMLRGYW G
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 93%.
Target Information
SQRDL (Sulfide: quinone oxidoreductase, mitochondrial) catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Although the SQRDL precursor protein displays a molecular weight of 50 kDa, a prominent band at about 46 kDa is detected by western blot. This discrepancy reflects the cleavage of an N-terminal targeting sequence of 4 kDa during the import of the protein into the mitochondria. SQRDL is one of the enzymes involved in H2S signaling in a discrete population of neurons, oligodendrocytes, and endothelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: flavo-binding protein; SQOR; sulfide dehydrogenase like; Sulfide dehydrogenase-like; Sulfide quinone oxidoreductase; Sulfide:quinone oxidoreductase, mitochondrial
Gene Aliases: 0610039J17Rik; 4930557M22Rik; CGI-44; PRO1975; SQOR; SQRDL
UniProt ID: (Human) Q9Y6N5, (Mouse) Q9R112
Entrez Gene ID: (Human) 58472, (Mouse) 59010
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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