Proteintech

SRA1 Polyclonal Antibody

SRA1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 7

SRA1 Antibody (24655-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed MCF-7 cells using 24655-1-AP (SRA1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

SRA1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

24655-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 7 publications 7 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:500

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SRA1 Fusion Protein Ag20082 (47-236 aa encoded by BC067895)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.51 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This polyclonal antibody recognizes endogenous SRA1 isoforms which migrate as a doublet on SDS-PAGE gels.

Immunogen sequence: GNKERGWND PPQFSYGLQT QAGGPRRSLL TKRVAAPQDG SPRVPASETS PGPPPMGPPP PSSKAPRSPP VGSGPASGVE PTSFPVESEA VMEDVLRPLE QALEDCRGHT RKQVCDDISR RLALLQEQWA GGKLSIPVKK RMALLVQELS SHRWDAADDI HRSLMVDHVT EVSQWMVGVK RLIAEKRSLF (47-236 aa encoded by BC067895)

Target Information

This gene is involved in transcriptional coactivation by steroid receptors. There is currently data suggesting this gene encodes both a non-coding RNA that functions as part of a ribonucleoprotein complex and a protein coding mRNA. Increased expression of both the transcript and the protein is associated with cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Magnetic resonance imaging of tumor-associated-macrophages (TAMs) with a nanoparticle contrast agent.

RSC advances

Zhou J,Meli VS,Yu-Tin Chen E,Kapre R,Nagalla R,Xiao W,Borowsky AD,Lam KS,Liu WF,Louie AY

Tue Mar 08 00:00:00 UTC 2022

Magnetic resonance imaging of tumor-associated-macrophages (TAMs) with a nanoparticle contrast agent.

RSC advances

Zhou J,Meli VS,Yu-Tin Chen E,Kapre R,Nagalla R,Xiao W,Borowsky AD,Lam KS,Liu WF,Louie AY

Tue Mar 08 00:00:00 UTC 2022

Effect of Si-Miao-Yong-An decoction on the differentiation of monocytes, macrophages, and regulatory T cells in ApoE^-/- mice.

Journal of ethnopharmacology

Chen XN,Ge QH,Zhao YX,Guo XC,Zhang JP

Tue Aug 10 00:00:00 UTC 2021

Up-regulation of thioredoxin system by puerarin inhibits lipid uptake in macrophages.

Free radical biology & medicine

Li W,Xu X,Dong D,Lei T,Ou H

Fri Jan 01 00:00:00 UTC 2021

VNN1 promotes atherosclerosis progression in apoE-/- mice fed a high-fat/high-cholesterol diet.

Journal of lipid research

Hu YW,Wu SG,Zhao JJ,Ma X,Lu JB,Xiu JC,Zhang Y,Huang C,Qiu YR,Sha YH,Gao JJ,Wang YC,Li SF,Zhao JY,Zheng L,Wang Q

Mon Aug 01 00:00:00 UTC 2016

VNN1 promotes atherosclerosis progression in apoE-/- mice fed a high-fat/high-cholesterol diet.

Journal of lipid research

Hu YW,Wu SG,Zhao JJ,Ma X,Lu JB,Xiu JC,Zhang Y,Huang C,Qiu YR,Sha YH,Gao JJ,Wang YC,Li SF,Zhao JY,Zheng L,Wang Q

Mon Aug 01 00:00:00 UTC 2016

RP5-833A20.1/miR-382-5p/NFIA-dependent signal transduction pathway contributes to the regulation of cholesterol homeostasis and inflammatory reaction.

Arteriosclerosis, thrombosis, and vascular biology

Hu YW,Zhao JY,Li SF,Huang JL,Qiu YR,Ma X,Wu SG,Chen ZP,Hu YR,Yang JY,Wang YC,Gao JJ,Sha YH,Zheng L,Wang Q

Thu Jan 01 00:00:00 UTC 2015

RP5-833A20.1/miR-382-5p/NFIA-dependent signal transduction pathway contributes to the regulation of cholesterol homeostasis and inflammatory reaction.

Arteriosclerosis, thrombosis, and vascular biology

Hu YW,Zhao JY,Li SF,Huang JL,Qiu YR,Ma X,Wu SG,Chen ZP,Hu YR,Yang JY,Wang YC,Gao JJ,Sha YH,Zheng L,Wang Q

Thu Jan 01 00:00:00 UTC 2015

RP5-833A20.1/miR-382-5p/NFIA-dependent signal transduction pathway contributes to the regulation of cholesterol homeostasis and inflammatory reaction.

Arteriosclerosis, thrombosis, and vascular biology

Hu YW,Zhao JY,Li SF,Huang JL,Qiu YR,Ma X,Wu SG,Chen ZP,Hu YR,Yang JY,Wang YC,Gao JJ,Sha YH,Zheng L,Wang Q

Thu Jan 01 00:00:00 UTC 2015

A lincRNA-DYNLRB2-2/GPR119/GLP-1R/ABCA1-dependent signal transduction pathway is essential for the regulation of cholesterol homeostasis.

Journal of lipid research

Hu YW,Yang JY,Ma X,Chen ZP,Hu YR,Zhao JY,Li SF,Qiu YR,Lu JB,Wang YC,Gao JJ,Sha YH,Zheng L,Wang Q

Tue Apr 01 00:00:00 UTC 2014

A lincRNA-DYNLRB2-2/GPR119/GLP-1R/ABCA1-dependent signal transduction pathway is essential for the regulation of cholesterol homeostasis.

Journal of lipid research

Hu YW,Yang JY,Ma X,Chen ZP,Hu YR,Zhao JY,Li SF,Qiu YR,Lu JB,Wang YC,Gao JJ,Sha YH,Zheng L,Wang Q

Tue Apr 01 00:00:00 UTC 2014

Dihydrocapsaicin Attenuates Plaque Formation through a PPARγ/LXRα Pathway in apoE(-/-) Mice Fed a High-Fat/High-Cholesterol Diet.

PloS one

Hu YW,Ma X,Huang JL,Mao XR,Yang JY,Zhao JY,Li SF,Qiu YR,Yang J,Zheng L,Wang Q

Thu Oct 12 00:00:00 UTC 2017

Dihydrocapsaicin Attenuates Plaque Formation through a PPARγ/LXRα Pathway in apoE(-/-) Mice Fed a High-Fat/High-Cholesterol Diet.

PloS one

Hu YW,Ma X,Huang JL,Mao XR,Yang JY,Zhao JY,Li SF,Qiu YR,Yang J,Zheng L,Wang Q

Thu Oct 12 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: MGC87674; SRA1; SRAP; steroid receptor coactivator; Steroid receptor RNA activator 1; steroid receptor RNA activator 1 (complexes with NCOA1); Steroid receptor RNA activator protein

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Gene Aliases: PP7684; SRA; SRA1; SRAP; STRAA1

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UniProt ID: (Human) Q9HD15

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Entrez Gene ID: (Human) 10011

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Function(s)

transcription coactivator activity protein binding ligand-dependent nuclear receptor binding ligand-dependent nuclear receptor transcription coactivator activity

Process(es)

transcription, DNA-templated regulation of transcription, DNA-templated apoptotic process cell proliferation cell differentiation regulation of apoptotic process positive regulation of receptor activity

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SRA1 Polyclonal Antibody

SRA1 Antibody (24655-1-AP) in ICC/IF

Product Details

24655-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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