Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
SRF Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
16821-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SRF Fusion Protein Ag10386 (1-348 aa encoded by BC048211)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLPTQAGAA AALGRGSALG GSLNRTPTGR PGGGGGTRGA NGGRVPGNGA GLGPGRLERE AAAAAATTPA PTAGALYSGS EGDSESGEEE ELGAERRGLK RSLSEMEIGM VVGGPEASAA ATGGYGPVSG AVSGAKPGKK TRGRVKIKME FIDNKLRRYT TFSKRKTGIM KKAYELSTLT GTQVLLLVAS ETGHVYTFAT RKLQPMITSE TGKALIQTCL NSPDSPPRSD PTTDQRMSAT GFEETDLTYQ VSESDSSGET KDTLKPAFTV TNLPGTTSTI QTAPSTSTTM QVSSGPSFPI TNYLAPVSAS VSPSAVSSAN GTVLKSTGSG PVSSGGLMQL PTSFTLMPG (1-348 aa encoded by BC048211 )
Target Information
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promotor elements in many muscle-specific promotors. SFR is required for cardiac differentiation and maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: c-fos serum response element-binding transcription factor; minichromosome maintenance 1 homolog; OTTHUMP00000039820; Serum response factor; serum response factor (c-fos serum response element-binding transcription factor); SRF
Gene Aliases: MCM1; SRF
UniProt ID: (Human) P11831
Entrez Gene ID: (Human) 6722
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
transcription factor activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
transcription factor binding
serum response element binding
chromatin DNA binding
protein homodimerization activity
histone deacetylase binding
primary miRNA binding
patterning of blood vessels
response to hypoxia
mesoderm formation
neuron migration
trophectodermal cell differentiation
heart looping
morphogenesis of an epithelial sheet
cell migration involved in sprouting angiogenesis
positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
transcription from RNA polymerase II promoter
cell-matrix adhesion
heart development
long-term memory
negative regulation of cell proliferation
associative learning
response to toxic substance
response to hormone
epithelial structure maintenance
positive regulation of transcription via serum response element binding
hippocampus development
tangential migration from the subventricular zone to the olfactory bulb
regulation of cell adhesion
platelet activation
platelet formation
negative regulation of cell migration
thyroid gland development
neuron projection development
regulation of water loss via skin
response to cytokine
megakaryocyte development
dorsal aorta morphogenesis
mRNA transcription from RNA polymerase II promoter
stress fiber assembly
skin morphogenesis
positive thymic T cell selection
sarcomere organization
positive regulation of cell differentiation
positive regulation of axon extension
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle contraction
positive regulation of transcription by glucose
muscle cell cellular homeostasis
thymus development
developmental growth
neuron development
erythrocyte development
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of smooth muscle cell differentiation
positive regulation of filopodium assembly
cardiac myofibril assembly
angiogenesis involved in wound healing
hematopoietic stem cell differentiation
positive regulation of transcription initiation from RNA polymerase II promoter
long term synaptic depression
face development
heart trabecula formation
lung morphogenesis
bronchus cartilage development
trachea cartilage development
cardiac vascular smooth muscle cell differentiation
eyelid development in camera-type eye
lung smooth muscle development
bicellular tight junction assembly
cellular response to glucose stimulus
primitive streak formation
epithelial cell-cell adhesion
cellular senescence
negative regulation of beta-amyloid clearance
negative regulation of pri-miRNA transcription from RNA polymerase II promoter
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support