Proteintech

SRP9 Polyclonal Antibody

SRP9 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SRP9 Antibody (11195-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human prostate cancer using 11195-1-AP (SRP9 antibody) at dilution of 1:100 (under 10x lens).

SRP9 Antibody in Immunoprecipitation (IP)

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Product Details

11195-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 9 publications 9 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SRP9 Fusion Protein Ag1683 (1-86 aa encoded by BC015094)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MPQYQTWEE FSRAAEKLYL ADPMKARVVL KYRHSDGNLC VKVTDDLVCL VYKTDQAQDV KKIEKFHSQL MRLMVAKEAR NVTMETE (1-86 aa encoded by B C015094)

Target Information

Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Alu RNA fold links splicing with signal recognition particle proteins.

Nucleic acids research

Borovská I,Vořechovský I,Královičová J

Fri Aug 25 00:00:00 UTC 2023

Investigation of SRP9 protein expression in breast cancer.

Molecular biology reports

Erdoğan G,Trabulus DC,Talu CK,Güven M

Sat Jan 01 00:00:00 UTC 2022

The pioneer round of translation ensures proper targeting of ER and mitochondrial proteins.

Nucleic acids research

Park J,Chang J,Hwang HJ,Jeong K,Lee HJ,Ha H,Park Y,Lim C,Woo JS,Kim YK

Thu Dec 02 00:00:00 UTC 2021

The noncoding RNA BC200 associates with polysomes to positively regulate mRNA translation in tumor cells.

The Journal of biological chemistry

Booy EP,Gussakovsky D,Choi T,McKenna SA

Fri Aug 27 00:00:00 UTC 2021

Comprehensive analysis of the BC200 ribonucleoprotein reveals a reciprocal regulatory function with CSDE1/UNR.

Nucleic acids research

Booy EP,McRae EK,Ezzati P,Choi T,Gussakovsky D,McKenna SA

Fri Nov 30 00:00:00 UTC 2018

Comprehensive analysis of the BC200 ribonucleoprotein reveals a reciprocal regulatory function with CSDE1/UNR.

Nucleic acids research

Booy EP,McRae EK,Ezzati P,Choi T,Gussakovsky D,McKenna SA

Fri Nov 30 00:00:00 UTC 2018

Comprehensive analysis of the BC200 ribonucleoprotein reveals a reciprocal regulatory function with CSDE1/UNR.

Nucleic acids research

Booy EP,McRae EK,Ezzati P,Choi T,Gussakovsky D,McKenna SA

Fri Nov 30 00:00:00 UTC 2018

Comprehensive analysis of the BC200 ribonucleoprotein reveals a reciprocal regulatory function with CSDE1/UNR.

Nucleic acids research

Booy EP,McRae EK,Ezzati P,Choi T,Gussakovsky D,McKenna SA

Fri Nov 30 00:00:00 UTC 2018

Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer.

Cell

Nabet BY,Qiu Y,Shabason JE,Wu TJ,Yoon T,Kim BC,Benci JL,DeMichele AM,Tchou J,Marcotrigiano J,Minn AJ

Thu Jul 13 00:00:00 UTC 2017

Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer.

Cell

Nabet BY,Qiu Y,Shabason JE,Wu TJ,Yoon T,Kim BC,Benci JL,DeMichele AM,Tchou J,Marcotrigiano J,Minn AJ

Thu Jul 13 00:00:00 UTC 2017

The CELF1 RNA-Binding Protein Regulates Decay of Signal Recognition Particle mRNAs and Limits Secretion in Mouse Myoblasts.

PloS one

Russo J,Lee JE,López CM,Anderson J,Nguyen TP,Heck AM,Wilusz J,Wilusz CJ

Mon Aug 14 00:00:00 UTC 2017

The CELF1 RNA-Binding Protein Regulates Decay of Signal Recognition Particle mRNAs and Limits Secretion in Mouse Myoblasts.

PloS one

Russo J,Lee JE,López CM,Anderson J,Nguyen TP,Heck AM,Wilusz J,Wilusz CJ

Mon Aug 14 00:00:00 UTC 2017

Identification of Srp9 as a febrile seizure susceptibility gene.

Annals of clinical and translational neurology

Hessel EV,de Wit M,Wolterink-Donselaar IG,Karst H,de Graaff E,van Lith HA,de Bruijn E,de Sonnaville S,Verbeek NE,Lindhout D,de Kovel CG,Koeleman BP,van Kempen M,Brilstra E,Cuppen E,Loos M,Spijker SS,Kan AA,Baars SE,van Rijen PC,Gosselaar PH,Groot Koerkamp MJ,Holstege FC,van Duijn C,Vergeer J,Moll HA,Taubøll E,Heuser K,Ramakers GM,Pasterkamp RJ,van Nieuwenhuizen O,Hoogenraad CC,Kas MJ,de Graan PN

Tue Apr 01 00:00:00 UTC 2014

Identification of Srp9 as a febrile seizure susceptibility gene.

Annals of clinical and translational neurology

Tue Apr 01 00:00:00 UTC 2014

Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle.

Nucleic acids research

Piazzon N,Schlotter F,Lefebvre S,Dodré M,Méreau A,Soret J,Besse A,Barkats M,Bordonné R,Branlant C,Massenet S

Tue Jan 01 00:00:00 UTC 2013

Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle.

Nucleic acids research

Piazzon N,Schlotter F,Lefebvre S,Dodré M,Méreau A,Soret J,Besse A,Barkats M,Bordonné R,Branlant C,Massenet S

Tue Jan 01 00:00:00 UTC 2013

Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle.

Nucleic acids research

Piazzon N,Schlotter F,Lefebvre S,Dodré M,Méreau A,Soret J,Besse A,Barkats M,Bordonné R,Branlant C,Massenet S

Tue Jan 01 00:00:00 UTC 2013

Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle.

Nucleic acids research

Piazzon N,Schlotter F,Lefebvre S,Dodré M,Méreau A,Soret J,Besse A,Barkats M,Bordonné R,Branlant C,Massenet S

Tue Jan 01 00:00:00 UTC 2013

Proteomic expression analysis of surgical human colorectal cancer tissues: up-regulation of PSB7, PRDX1, and SRP9 and hypoxic adaptation in cancer.

Journal of proteome research

Rho JH,Qin S,Wang JY,Roehrl MH

Tue Jul 01 00:00:00 UTC 2008

Proteomic expression analysis of surgical human colorectal cancer tissues: up-regulation of PSB7, PRDX1, and SRP9 and hypoxic adaptation in cancer.

Journal of proteome research

Rho JH,Qin S,Wang JY,Roehrl MH

Tue Jul 01 00:00:00 UTC 2008

Bioinformatics

Protein Aliases: Signal recognition particle 9 kDa protein; signal recognition particle 9kD; signal recognition particle 9kDa; SRP9

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Gene Aliases: 9kDa; ALURBP; SRP9

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UniProt ID: (Human) P49458, (Mouse) P49962

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Entrez Gene ID: (Human) 6726, (Rat) 690345, (Mouse) 27058

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Function(s)

RNA binding signal recognition particle binding protein binding 7S RNA binding

Process(es)

SRP-dependent cotranslational protein targeting to membrane negative regulation of translational elongation SRP-dependent cotranslational protein targeting to membrane, translocation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SRP9 Polyclonal Antibody

SRP9 Antibody (11195-1-AP) in IHC (P)

Product Details

11195-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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