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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SRPRB Antibodies

          Proteintech

          SRPRB Polyclonal Antibody

          1 Reference
          View all (24) SRPRB antibodies

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          Cite SRPRB Polyclonal Antibody

          • Antibody Testing Data (5)
          SRPRB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          SRPRB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 5

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          SRPRB Antibody (14636-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded human liver tissue slide using (Product # 14636-1-AP) (SRPRB antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SRPRB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SRPRB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SRPRB Antibody in Western Blot (WB)
          SRPRB Antibody in Western Blot (WB)
          SRPRB Antibody in Western Blot (WB)

          Product Details

          14636-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          SRPRB Fusion Protein Ag6215 (1-271 aa encoded by BC065299)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.13 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MASADSRRV ADGGGAGGTF QPYLDTLRQE LQQTDPTLLS VVVAVLAVLL TLVFWKLIRS RRSSQRAVLL VGLCDSGKTL LFVRLLTGLY RDTQTSITDS CAVYRVNNNR GNSLTLIDLP GHESLRLQFL ERFKSSARAI VFVVDSAAFQ REVKDVAEFL YQVLIDSMGL KNTPSFLIAC NKQDIAMAKS AKLIQQQLEK ELNTLRVTRS AAPSTLDSSS TAPAQLGKKG KEFEFSQLPL KVEFLECSAK GGRGDVGSAD IQDLEKWLAK IA (1-271 aa encoded by BC065299)

          Target Information

          SRPRB has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane. The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane. The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Protein APMCF1; Signal recognition particle receptor subunit beta; signal recognition particle receptor, B subunit; signal recognition particle receptor, beta subunit; SR-beta

          View more View less

          Gene Aliases: AA409543; Ab2-417; APMCF1; Ba1-667; Cc1-8; PSEC0230; SRPRB

          View more View less

          UniProt ID: (Human) Q9Y5M8, (Rat) Q4FZX7, (Mouse) P47758

          View more View less

          Entrez Gene ID: (Human) 58477, (Rat) 300965, (Mouse) 20818

          View more View less

          Function(s)
          signal recognition particle binding GTP binding ubiquitin protein ligase binding nucleotide binding
          Process(es)
          SRP-dependent cotranslational protein targeting to membrane small GTPase mediated signal transduction IRE1-mediated unfolded protein response retina homeostasis
          It has to be done as per old AB suggested Products section.
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