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Invitrogen
SRPX2 Polyclonal Antibody
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Product Details
PA5-83439
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SRPX2. Recombinant protein control fragment (Product #RP-95439).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2790594
Product Specific Information
Immunogen sequence: ESYNEVYAEE VPQAPALDYR VPRWCYTLNI QDGEATCYSP KGGNYHSSLG TRCELSCDRG FRLIGRRSVQ CLPSRRWSGT AYCRQMRCHA LPFIT
Target Information
Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain; mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation and cognitive disorders. Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, a protein that can facilitate invasive migration of sprouting endothelial cells. SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion, suggesting that SRPX2 may be a potential target in the treatment of metastatic cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RP11-524D16__A.1; Sushi repeat-containing protein SRPX2; sushi-repeat containing protein, X-linked 2; sushi-repeat protein up-regulated in leukemia; Sushi-repeat protein upregulated in leukemia; sushi-repeat-containing protein, X-linked 2
Gene Aliases: BPP; CBPS; PMGX; RESDX; SRPUL; SRPX2
UniProt ID: (Human) O60687
Entrez Gene ID: (Human) 27286
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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