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Proteintech
SRRM1 Polyclonal Antibody
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Product Details
12822-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SRRM1 Fusion Protein Ag3513 (1-350 aa encoded by BC036187)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is a rabbit polyclonal antibody raised against residues near the N terminus of human SRRM1.
Immunogen sequence: MDAGFFRGT SAEQDNRFSN KQKKLLKQLK FAECLEKKVD MSKVNLEVIK PWITKRVTEI LGFEDDVVIE FIFNQLEVKN PDSKMMQINL TGFLNGKNAR EFMGELWPLL LSAQENIAGI PSAFLELKKE EIKQRQIEQE KLASMKKQDE DKDKRDKEEK ESSREKRERS HSPRRRKSRS PSPRRRSSPV RRERKRSHSR SPRHRTKSRS PSPAPEKKEK TPELPEPSVK VKEPSVQEAT STSDILKVPK PEPIPEPKEP SPEKNSKKEK EKEKTQPRSR SRSKSRSRTR SRSPSHTRPR RRHRSRSRSY SPRRRPSPRR RPSPRRRTPP RRMPPPPRHR RSRSPVRRRR R (1-350 aa encoded by BC036187)
Target Information
Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Plenty-of-prolines 101; plenty-of-prolines-101; Ser/Arg-related nuclear matrix protein; serine/arginine repetitive matrix 1; Serine/arginine repetitive matrix protein 1; SR-related nuclear matrix protein of 160 kDa; SRm160
Gene Aliases: 160-KD; AA407769; POP101; SRM160; SRRM1
UniProt ID: (Human) Q8IYB3, (Mouse) Q52KI8
Entrez Gene ID: (Human) 10250, (Mouse) 51796, (Rat) 313620
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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