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SRRM2 Antibody (PA5-68009) in WB
The Journal of cell biology 2020 -
Figure S3. MFAP1 KD specifically increases nuclear speckle size. (A) Western blots showing RNAi depletion of the indicated proteins (SRRM2, ZNF207, or PRPF38A) in U2OS cells. (B and C) Western blot showing the depletion of MFAP1 in Tig3 (B) or CHO (C) cells. Tubulin was detected as loading control. (D) Representative anti-SON immunofluorescence images of U2OS cells following siRNA treatment as indicated. (E... View More
Product Details
PA5-68009
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human SRRM2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2691852
Product Specific Information
Predicted to react with Mouse samples.
Target Information
SRRM2 is involved in pre-mRNA splicing. It may function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome and may do so by stabilizing the catalytic center or the position of the RNA substrate. It binds to RNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 300 kDa nuclear matrix antigen; RNA binding protein; ser/Arg-related nuclear matrix protein of 300 kDa; Serine/arginine repetitive matrix protein 2; Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa; Splicing coactivator subunit SRm300; SR-related nuclear matrix protein of 300 kDa; Tax-responsive enhancer element-binding protein 803; TaxREB803; testicular secretory protein Li 53
Gene Aliases: 300-KD; 5033413A03Rik; AA410130; Cwc21; CWF21; HSPC075; KIAA0324; mKIAA0324; SRL300; SRM300; SRRM2
UniProt ID: (Human) Q9UQ35, (Mouse) Q8BTI8
Entrez Gene ID: (Human) 23524, (Mouse) 75956
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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