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SRSF11 Antibody (PA5-116829) in IHC (P)
Immunohistochemistry analysis of SRSF11 in paraffin-embedded human breast. Samples were incubated with SRSF11 Polyclonal antibody (Product # PA5-116829) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-116829
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 396-483 of human SRSF11 (NP_001177916)
Conjugate
Form
Liquid
Concentration
0.03 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2901460
Product Specific Information
Positive Samples: Rat lung
Immunogen sequence: SKKKKSKDKE KDRERKSESD KDVKVTRDYD EEEQGYDSEK EKKEEKKPIE TGSPKTKECS VEKGTGDSLR ESKVNGDDHH EEDMDMSD
Target Information
Pre-mRNA splicing enhancer elements are short RNA sequences capable of activating weak splice sites in nearby introns that are required for accurate splice site recognition and the control of alternative splicing. Splicing enhancer elements contain specific binding sites for serine/arginine (SR)-rich splicing factors, which include SC35, 9G8, SRp20 and SF2/ASF. The family of SR factors all contain one or more RNA recognition motifs (RRM) and a SR-rich domain. The SR factor family is not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. SFRS11 (splicing factor, arginine/serine-rich 11), also known as arginine-rich 54 kDa nuclear protein (p54) or NET2, is a 484 amino acid nuclear protein that colocalizes with spliceosome components and belongs to the splicing factor SR family. SFRS11 may function in pre-mRNA splicing and contains one RRM (RNA recognition motif) domain.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Arginine-rich 54 kDa nuclear protein; p54; Serine/arginine-rich splicing factor 11; SFR11; splicing factor p54; Splicing factor, arginine/serine-rich 11; SR splicing factor 11
Gene Aliases: 0610009J05Rik; 2610019N13Rik; BF642805; dJ677H15.2; NET2; p54; SFRS11; SRSF11
UniProt ID: (Human) Q5T758
Entrez Gene ID: (Human) 9295, (Mouse) 69207, (Rat) 502603
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