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Invitrogen
SRSF6 Polyclonal Antibody
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SRSF6 Antibody (PA5-89933) in WB
Western blot analysis of SRSF6 in extracts of various cell lines. Samples were incubated with SRSF6 Polyclonal antibody (Product # PA5-89933) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-89933
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SRSF6 (NP_0062662)
Conjugate
Form
Liquid
Concentration
0.93 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2805850
Product Specific Information
Immunogen sequence: MPRVYIGRLS YNVREKDIQR FFSGYGRLLE VDLKNGYGFV EFEDSRDADD AVYELNGKEL CGERVIVEHA RGPRRDRDGY SYGSRSGGGG YSSRRTSGRD; Positive Samples: HT-29, K562, HeLa, HepG2; Cellular Location: Nucleus, Nucleus speckle
Target Information
SFRS6 is involved in mRNA splicing and may play a role in the determination of alternative splicing. It belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory protein Li 91; MGC5045; Pre-mRNA-splicing factor SRP55; Serine/arginine-rich splicing factor 6; Splicing factor, arginine/serine-rich 6; splicing factor, arginine/serine-rich, 55 kDa; SR splicing factor 6
Gene Aliases: 1210001E11Rik; AI314910; AW146126; B52; HEL-S-91; SFRS6; SRP55; SRSF6
UniProt ID: (Human) Q13247, (Rat) G3V6S8, (Mouse) Q3TWW8
Entrez Gene ID: (Human) 6431, (Rat) 362264, (Mouse) 67996
alternative mRNA splicing, via spliceosome
regulation of alternative mRNA splicing, via spliceosome
mRNA splicing, via spliceosome
termination of RNA polymerase II transcription
mRNA splice site selection
RNA export from nucleus
mRNA export from nucleus
regulation of keratinocyte proliferation
mRNA 3'-end processing
negative regulation of keratinocyte differentiation
negative regulation of mRNA splicing, via spliceosome
positive regulation of epithelial cell proliferation involved in lung morphogenesis
negative regulation of cell death
regulation of wound healing
mRNA processing
RNA splicing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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