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Bethyl Laboratories
SRp55 Polyclonal Antibody
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SRp55 Antibody (A303-669A) in IHC (P)
Detection of human SRp55 by immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-SRp55 (Product # A303-669A) (Lot 1) used at a dilution of 1:1,000 (1 µg/mL). Detection: DAB. Counterstain: Hematoxylin (blue).
Product Details
A303-669A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 250 and 300 of Human Splicing Factor, Arginine/Serine-Rich, 55 kDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Bovine
Target Information
SFRS6 is involved in mRNA splicing and may play a role in the determination of alternative splicing. It belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory protein Li 91; MGC5045; Pre-mRNA-splicing factor SRP55; Serine/arginine-rich splicing factor 6; Splicing factor, arginine/serine-rich 6; splicing factor, arginine/serine-rich, 55 kDa; SR splicing factor 6
Gene Aliases: 1210001E11Rik; AI314910; AW146126; B52; HEL-S-91; SFRS6; SRP55; SRSF6
UniProt ID: (Human) Q13247, (Mouse) Q3TWW8
Entrez Gene ID: (Human) 6431, (Mouse) 67996
alternative mRNA splicing, via spliceosome
regulation of alternative mRNA splicing, via spliceosome
mRNA splicing, via spliceosome
termination of RNA polymerase II transcription
mRNA splice site selection
RNA export from nucleus
mRNA export from nucleus
regulation of keratinocyte proliferation
mRNA 3'-end processing
negative regulation of keratinocyte differentiation
negative regulation of mRNA splicing, via spliceosome
positive regulation of epithelial cell proliferation involved in lung morphogenesis
negative regulation of cell death
regulation of wound healing
mRNA processing
RNA splicing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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