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SSTR1 Antibody (704008) in ICC/IF
HEK-293 cells stably transfected with SSTR1 were grown on poly-L-lysine-coated coverslips overnight. After 24 h, cells were fixed with 4% paraformaldehyde and 0.2% picric acid in phosphate buffer (pH 6.9) for 30 min at room temperature and washed several times with phosphate buffer. Specimens were permeabilized with ice-cold methanol and then incubated with SSTR1 Recombinant Rabbit Monoclonal Antibody (Product # 704008, 1:1,000 dilution). Cells were then incubated with Alexa488-conjugated secondary antibody for 2 h at room temperature, mou... View More
Product Details
704008
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
18H22L9
Immunogen
Peptide corresponding to the aa residues 377-391 of the human SSTR1.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3073993
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include better specificity and lot-to-lot consistency.
It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Target Information
Somatostatin acts to regulate numerous physiological processes by binding to and activating specific receptors in target tissues. Activation of these receptors by somatostatin, which is secreted by nerve and endocrine cells, regulates the secretion of insulin, glucagon and growth hormone, neuronal excitability in both the brain and the peripheral nervous system, and cell growth. Somatostatin receptors have been implicated in numerous diseases ranging from Alzheimer's to cancers of the gastrointestinal tract, breast, prostate, and pituitary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RNGPCRRNA; somatostatin receptor; Somatostatin receptor subtype 1; Somatostatin receptor type 1; SRIF-2; SS-1-R; SS1-R; SS1R; Sst1 receptor
Gene Aliases: Gpcrrna; Smstr-1; Smstr1; SRIF-2; SS-1-R; SS1-R; SS1R; sst1; SSTR1
UniProt ID: (Human) P30872, (Mouse) P30873, (Rat) P28646
Entrez Gene ID: (Human) 6751, (Mouse) 20605, (Rat) 25033
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
glutamate receptor signaling pathway
neuropeptide signaling pathway
cell-cell signaling
chemical synaptic transmission
spermatogenesis
response to nutrient
digestion
negative regulation of cell proliferation
cerebellum development
forebrain development
somatostatin signaling pathway
response to starvation
cellular response to estradiol stimulus
signal transduction
G-protein coupled receptor signaling pathway
T cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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