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Product Details
H00008869-M04
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
8B4
Immunogen
ST3GAL5 (NP_003887, 31 a.a. approximately 117 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: YTTEECDMKK MHYVDPDHVK RAQKYAQQVL QKECRPKFAK TSMALLFEHR YSVDLLPFVQ KAPKDSEAES KYDPPFGFRK FSSKVQT
Target Information
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha 2,3-sialyltransferase V; CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; Ganglioside GM3 synthase; GM3 synthase; Lactosylceramide alpha-2,3-sialyltransferase; Sialyltransferase 9; sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase); ST3 beta-galactoside alpha-23-sialyltransferase 5; ST3Gal V; ST3GalV
Gene Aliases: SATI; SIAT9; SIATGM3S; ST3GAL5; ST3GalV; UNQ2510/PRO5998
UniProt ID: (Human) Q9UNP4
Entrez Gene ID: (Human) 8869
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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