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Invitrogen
ST3GAL6 Polyclonal Antibody
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Product Details
PA5-53845
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ST3GAL6. Recombinant protein control fragment (Product #RP-89966).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2647969
Product Specific Information
Immunogen sequence: IQPCLSKPAF ASLLRFHQFH PFLCAADFRK IASLYGSDKF DLPYGMRTSA EYFRLALSKL QSCDLFDEFD NIPCKKCVVV GNGGVLKNKT LGEKIDSYDV IIRMNNG
Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 75%.
Target Information
Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha2,3-sialyltransferase ST3Gal VI; CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI; sia10; Sialyltransferase 10; sialyltransferase 10 (alpha-2,3-sialyltransferase VI); ST3Gal VI; ST3GalVI; Type 2 lactosamine alpha-2,3-sialyltransferase
Gene Aliases: SIAT10; ST3GAL6; ST3GALVI
UniProt ID: (Human) Q9Y274
Entrez Gene ID: (Human) 10402
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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